ID   KUP2_POLSJ              Reviewed;         622 AA.
AC   Q122S7;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Bpro_4582;
OS   Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas; unclassified Polaromonas.
OX   NCBI_TaxID=296591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS666 / ATCC BAA-500;
RX   PubMed=18723656; DOI=10.1128/aem.00197-08;
RA   Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA   Stothard P., Coleman N.V.;
RT   "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT   a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT   relevance to biotechnology.";
RL   Appl. Environ. Microbiol. 74:6405-6416(2008).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000316; ABE46465.1; -; Genomic_DNA.
DR   RefSeq; WP_011485452.1; NC_007948.1.
DR   AlphaFoldDB; Q122S7; -.
DR   STRING; 296591.Bpro_4582; -.
DR   EnsemblBacteria; ABE46465; ABE46465; Bpro_4582.
DR   KEGG; pol:Bpro_4582; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000001983; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..622
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_5000117283"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        337..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   622 AA;  67676 MW;  7A8BEC6874D25319 CRC64;
     MSSKKSSLAA LTLGAIGVVY GDIGTSVLYA IKEVFGSGHV PFTPGNIYGI LSIFFWTLTV
     IVSIKYVVLV LRADNNGEGG LIAMLALAST AVKDKPKLRR ILLIVGVFGT SLFYGDGVIT
     PAISVLSAVE GLEVVSPAFK EGVIPITLVI LFCLFALQKH GTAGIGRYFG PITLIWFVVI
     ALLGISQIVT NPAILKAISP HYALLFMWHN PGTTFIILGA VVLCVTGAEA LYADLGHFGK
     RPIRLAWFSV VMPSLVLNYF GQGALLLNNP AAVKNPFYLM APEWALLPLV GLATMATVIA
     SQAMITGAFS VTKQAVQMGY LPRLNIQHTS VKDTGQIYIT FVNWSLFVAI VLAVVMFRSS
     SNLAAAYGIA VTLDMLITTT LTFFVIRYSW NYPLSLCIAA TGVFFLVDLA FFASNLMKLF
     AGGWFPLLIG GAVFTLMMTW KEGRGLLNDK LRSDAIDLPS FLDAVFVSPP ARVEGTAVFL
     TAEPGTVPNA MLHNLKHNKV LHQQNLFVTV RYHEVPWIGM NKRLEIESLG HDCWQVTVHY
     GFKNDLDLPK ALQQIKGRGC ELESMTTSYF LSRDTVVPTI GRGMASWREK LFAQMHHNAS
     GAADFLNLPN NSVVELGSKI EI