ID   KUP2_RHIEC              Reviewed;         633 AA.
AC   Q2K711;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=RHE_CH02603;
OS   Rhizobium etli (strain CFN 42 / ATCC 51251).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFN 42 / ATCC 51251;
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT   seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000133; ABC91375.1; -; Genomic_DNA.
DR   RefSeq; WP_011425853.1; NC_007761.1.
DR   AlphaFoldDB; Q2K711; -.
DR   STRING; 347834.RHE_CH02603; -.
DR   EnsemblBacteria; ABC91375; ABC91375; RHE_CH02603.
DR   GeneID; 61481022; -.
DR   KEGG; ret:RHE_CH02603; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; LMIMCIV; -.
DR   Proteomes; UP000001936; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..633
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_0000279819"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        402..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        429..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   633 AA;  68996 MW;  DF11D55D9EC78C30 CRC64;
     MTSTHADKTG DVASRTGFVG LVVGAIGVVY GDIGTSPLYA FREALRPFTA DGVHEFEVIG
     LISLMIWTLT IIVTFKYVLF LLRADNDGEG GTLSLLALLM KKMGRNVPVL FFAGLIGSAL
     FIGDAMITPA LSVMSALEGL KLITPAFAEY VPPLSAAIMI VLFAAQSRGT AAVSMFFGPI
     TVLWFFAMAA GGVIHIGDDW RILAAINPIN ALSFLAHAGT VGLIVLGAVF LTVTGAEALY
     ADLGHFGRRP IQMAWFVLVF PALLLNYLGQ GALVLSQPAA SADPFFLMYP DWALLPVVLL
     ATLATIIASQ AVITGAFSLA RQAVHLGFLP RLRIKFTSET NTGQIYVPSV NLLLLTGVLM
     LIFSFGDSES LATAYGISVT GAMVITTMLA FQFLRAVWGY SFMLASAALL PLFVIEVVFL
     AANLLKIQDG GWVPVALALA IMTLMWTWTR GQTYLKKLRA NNEIPLDSFI RSIERKSDHS
     PVTVPGTAVF LTSVPDRTPN VLLHNLKHNH VLHEQNVILT VWTEDEPYVP DNRRIKISQL
     SPRFVRLDIN FGFMDDPDVT RALALCREGG FKFEIMKTSF YLGRRNLVRT PNTGLPGWQE
     RIFMALEGFA IDPSDYFNLP SNRVVELGEQ VAI