ID   KUP2_RHIL3              Reviewed;         633 AA.
AC   Q1MEX2;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=RL3014;
OS   Rhizobium leguminosarum bv. viciae (strain 3841).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=216596;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3841;
RX   PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34;
RA   Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F.,
RA   Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H.,
RA   East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach I.,
RA   Chillingworth T., Clarke K., Cronin A., Davis P., Fraser A., Hance Z.,
RA   Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA   Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J.;
RT   "The genome of Rhizobium leguminosarum has recognizable core and accessory
RT   components.";
RL   Genome Biol. 7:R34.1-R34.20(2006).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; AM236080; CAK08502.1; -; Genomic_DNA.
DR   RefSeq; WP_011652529.1; NC_008380.1.
DR   AlphaFoldDB; Q1MEX2; -.
DR   STRING; 216596.RL3014; -.
DR   PRIDE; Q1MEX2; -.
DR   EnsemblBacteria; CAK08502; CAK08502; RL3014.
DR   KEGG; rle:RL3014; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; LMIMCIV; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000006575; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..633
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_0000279822"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        402..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   633 AA;  68779 MW;  9D29F54063527C66 CRC64;
     MTSTHMDKTG DGAGRKGFVG LVIGAVGVVY GDIGTSPLYA LREALRPFAA DGVHEAEVIG
     LISLMVWTLT IIVTFKYVLF LLRADNDGEG GTLSLLALLM KKMGRNVPVL FFAGLIGAAL
     FIGDAMITPA LSVMSALEGL KLITPAFAEY VPLASAAIMI VLFAVQSRGT AAVSKLFGPI
     TVLWFLAMAA GGVIHIGDDW RILAALNPLT ALSFLAHAGS VGLIVLGAVF LTVTGAEALY
     ADLGHFGRRP IQMAWFVLVF PALLLNYLGQ GALVLAHPEA ATNPFFLMYP DWALLPVVIL
     ATMATIIASQ AVITGAFSLA RSAVHLGFLP RLRIKFTSET NTGQIYVPSV NLLLLVGVLM
     LISSFGDSES LATAYGISVT GTMVISTMLA FQFLRAVWGY SLVVAAVLLL PLFIIEVLFL
     AANLLKIHDG GWVPVALALA IMIMMWTWTR GQAYLKRLRA NNEIPLDSFI RSIERKSDHS
     PVTVPGTAVF LTSVPDRTPN VLLHNLKHNH VLHEQNVILT VWTEDEPYVP DSRRIKISQL
     SPRFVRLDIT FGFMDDPDVT RALALCRESG FKFEIMKTSF YLGRRNLVRT PNTGLPGWQE
     RIFVVLEGFA IDPSDYFNLP SNRVVELGEQ IAI