ID   KUP2_SINMW              Reviewed;         633 AA.
AC   A6UM20;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Smed_6041;
OS   Sinorhizobium medicae (strain WSM419) (Ensifer medicae).
OG   Plasmid pSMED02.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=366394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM419;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G.,
RA   Richardson P.;
RT   "Complete sequence of Sinorhizobium medicae WSM419 plasmid pSMED02.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000740; ABR64700.1; -; Genomic_DNA.
DR   RefSeq; WP_011970808.1; NC_009621.1.
DR   RefSeq; YP_001314633.1; NC_009621.1.
DR   AlphaFoldDB; A6UM20; -.
DR   STRING; 366394.Smed_6041; -.
DR   EnsemblBacteria; ABR64700; ABR64700; Smed_6041.
DR   KEGG; smd:Smed_6041; -.
DR   PATRIC; fig|366394.8.peg.2549; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; FDTCMVT; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000001108; Plasmid pSMED02.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Plasmid;
KW   Potassium; Potassium transport; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..633
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_0000315991"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        405..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   633 AA;  68885 MW;  54DE2BBFF156867B CRC64;
     MADSLDHAPA QANNLPQFLA MTIGAIGVVY GDIGTSPLYA FREALRPFGP DGVERAEVVG
     LISLMLWTLT IIVTFKYVLF LLRADNDGEG GTLSLLALLM KKAPRYTTLM FMAGILGAAL
     FIGDAMITPA LSVLSAVEGL KLVTPAFHDY VLPISVGIMV LLFAVQSRGT GAVSIFFGPI
     TLIWFLVLGA AGVAHIGDDL AILAAFNPVN AVTFLWNAGF VGFIVLGAVF LTVTGAEALY
     ADLGHFGRGP IQAAWFAVVF PALTLNYLGQ GALVLSHPEA VSDPFFLMFP NWALLPVVLL
     ATAATIIASQ AVITGAFSLV RQAINLGFLP RFEICFTSET QTGQIYLPFV NNALLAGVIV
     LMFMFGSSES LATAYGISVT GAMVVTTVLA FEFARHQWGW STLTATAVLL PLLVLELFFL
     GANLFKIHDG GYVPILIAGT LMTTMWTWRK GVSLLREKTA RQDIPLSQFM AMVERKSEHA
     PVEVPGTAIF LTATPDTTPA VLLHNIKHNH VLHQHNVILT IKTARVPYVP EKDRYTIEKL
     SDRFSLLELR FGFMDDQNVS RALARCRKEG FKFEIMSTSF YLGRRKLIAA PQSGLPQWQD
     KLFIAMADSA IDPTEYFHLP PNRVVELGEQ VVI