ID   KUP3_GEOSL              Reviewed;         605 AA.
AC   Q747C1;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2013, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Probable potassium transport system protein kup 3 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup3 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=GSU3346;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; AE017180; AAR36736.2; -; Genomic_DNA.
DR   RefSeq; NP_954386.2; NC_002939.5.
DR   RefSeq; WP_010943958.1; NC_002939.5.
DR   AlphaFoldDB; Q747C1; -.
DR   STRING; 243231.GSU3346; -.
DR   EnsemblBacteria; AAR36736; AAR36736; GSU3346.
DR   KEGG; gsu:GSU3346; -.
DR   PATRIC; fig|243231.5.peg.3367; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_7; -.
DR   InParanoid; Q747C1; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 2.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..605
FT                   /note="Probable potassium transport system protein kup 3"
FT                   /id="PRO_0000209018"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        397..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        418..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   605 AA;  66417 MW;  D3360E019C7F6C7B CRC64;
     MEHHKHDTFL GGIVKALGLV FGDIGTSPIY TLTVIFTLTQ PTIDNVYGIL SLIFWTMTIL
     VSAEYAWLAM SLGRKGQGGE IVLREIIMKL VKAGRLVAFA GFLSFVGVSL LLGDAVITPA
     ISILSAVEGL LLIPGLEGLS TGALVAIAAA IAIGLFSVQH KGTDRVASAF GPIMALWFGT
     LAVTGAVSAF SMPQIVEAIN PLHGIAFFRD NGLAGYFVLS EVILCATGGE ALYADMGHLG
     KRPIVRAWHF VFVALYLNYL GQGVFAIAHP DAKNLLFGMV RSQAPALYIP FLILTIMATI
     IASQAIISGV FSIVYQGITT RLLPLMRVDY TSRQIKSQIY LGAVNWSLMV AVIFIMLVFR
     KSENLAAAYG MAVTGSMTIT GIMMIIVFSH TTKKWRALVA LVVTLIAAAY HVSTFSKLPH
     GAYWSIILAS IPFVTIIIWT RGQRTLYRAL KPLDLETFLI SYEQIYAKGP IRGTGLFFTR
     ETDVVPPYVV HCIIRSNIIY ERNVFISLMI SDEPLGVETE LIRGIGPGLD AFRIEAGYME
     MVDIERLLKE NGIQEKVIFY GVEDISTRNP FWRFFSVLKK LTPNFVQFHK LPASRLQGVV
     TRVEM