ID   KUP3_LEGPA              Reviewed;         629 AA.
AC   Q5X2E7;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Probable potassium transport system protein kup 3 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup3 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=lpp2446;
OS   Legionella pneumophila (strain Paris).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=297246;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Paris;
RX   PubMed=15467720; DOI=10.1038/ng1447;
RA   Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L.,
RA   Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J.,
RA   Glaser P., Buchrieser C.;
RT   "Evidence in the Legionella pneumophila genome for exploitation of host
RT   cell functions and high genome plasticity.";
RL   Nat. Genet. 36:1165-1173(2004).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CR628336; CAH13599.1; -; Genomic_DNA.
DR   RefSeq; WP_015961562.1; NC_006368.1.
DR   AlphaFoldDB; Q5X2E7; -.
DR   KEGG; lpp:lpp2446; -.
DR   LegioList; lpp2446; -.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   OMA; FDTCMVT; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..629
FT                   /note="Probable potassium transport system protein kup 3"
FT                   /id="PRO_0000209031"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   629 AA;  68820 MW;  02814BD534441390 CRC64;
     MPSTRNIEKH NDSNPTLRAL SLSALGIVYG DIGTSPLYTF KTVILLAGGG TPDVTTIMGS
     ASLIIWTLII IASVKYICFA LRIDNDGEGG ILALMSLLSL KLKQKPFIIA VGLMGAALIY
     GDGTITPAIS VLSAVEGLEI LSPSLKYYVL PIAITILITL FAIQSKGTTT IGKAFGPVMA
     FWFLTIGILG ARGVIQHPFV LAAINPVYGL NFLFSNGATG FFILCGVFLC ATGAEALYAD
     LGHFGTAPIR CTWFGLAFPS LIFNYLGQAA LVLEGASTEH NIFYMLCPSD FLLPLIILST
     VATIIASQAI ITGAFSMTRQ AMQLGWLPRL RVTQTSSEGY GQIYIGVVNW LLMLATLGLI
     IGFGSSEKLA AAYGIAVSAT MLCTTVLLFI ALHKLWKWNI ITSGLVAGLF MIVDASFFAA
     NLTKFINGGY IPITLAIIIY SMMYIWHKGY KTIAIKQKEK NITVDSFLDS IQKEGVVRVS
     KTAVFLTSKE QDIPPTLVWH VKKNHVLQDK VIILNINNLS IPWCKPGDQL QIVETGAGIW
     HAVANYGFME QPHIPKLLKK LEAQGYDINI KDITYYIGHE TIFVRNARHT LSKYIKILFV
     FMHRNALPMS NYFHLPPESV FEIGRQIEI