ID   KUP3_LEGPH              Reviewed;         629 AA.
AC   Q5ZSY2;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 2.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Probable potassium transport system protein kup 3 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup3 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=lpg2384;
OS   Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS   33152 / DSM 7513).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=272624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513;
RX   PubMed=15448271; DOI=10.1126/science.1099776;
RA   Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA   Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA   Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA   Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA   Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA   Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA   Russo J.J.;
RT   "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL   Science 305:1966-1968(2004).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAU28445.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE017354; AAU28445.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_016357009.1; NC_002942.5.
DR   RefSeq; YP_096392.1; NC_002942.5.
DR   AlphaFoldDB; Q5ZSY2; -.
DR   STRING; 272624.lpg2384; -.
DR   PaxDb; Q5ZSY2; -.
DR   PRIDE; Q5ZSY2; -.
DR   EnsemblBacteria; AAU28445; AAU28445; lpg2384.
DR   KEGG; lpn:lpg2384; -.
DR   PATRIC; fig|272624.6.peg.2516; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   Proteomes; UP000000609; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..629
FT                   /note="Probable potassium transport system protein kup 3"
FT                   /id="PRO_0000209034"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   629 AA;  68868 MW;  0062F4238AD74660 CRC64;
     MPSTRNIETH NDSNPTLRAL SLSALGIVYG DIGTSPLYTF KTVILLAGGG TPAVNTIMGS
     VSLIIWTLII IASVKYIHFA LRIDNDGEGG ILALMSLLSL KLKQRPFIIA VGLMGAALIY
     GDGTITPAIS VLSAVEGLEI LSPSLKYYVL PIAITILITL FAIQSKGTAT IGKAFGPVMA
     FWFLTIGILG ARGVIQHPSV LAAINPIYGL SFLFSNGATG FFILCGVFLC VTGAEALYAD
     LGHFGTAPIR CAWFGLAFPS LIFNYLGQAA LVLEGASTEH NIFYMLCPGD FLLPLIILST
     VATIIASQAI ITGAFSMTRQ AMQLGWLPRL RVTQTSSEGY GQIYIGVVNW LLMLATLGLT
     IGFGSSEKLA AAYGIAVSAT MLCTTLLLFI ALHKLWKWDI ITSGLVAGLF MIVDASFFAA
     NLTKFINGGY IPITLAIIIY SMMYIWHKGY QTIAIKQKEK NITVASFLDS IQKERVVRVP
     KTAVFLTSKE QDIPPILVWH VKKNHVLQDK VIILKINNLS IPRCKPGDRL QIVETGTGIW
     HAVANYGFME QPHIPKLLKK LEAQGYDINI KDITYYIGHE TIFVRNVRHT LSKYIKILFV
     FMHRNALPMS NYFHLPPESV FEIGRQIEI