ID   KUP_ACIAC               Reviewed;         622 AA.
AC   A1TVU0;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Aave_4541;
OS   Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Acidovorax.
OX   NCBI_TaxID=397945;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AAC00-1;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.;
RT   "Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000512; ABM35078.1; -; Genomic_DNA.
DR   RefSeq; WP_011797546.1; NC_008752.1.
DR   AlphaFoldDB; A1TVU0; -.
DR   STRING; 397945.Aave_4541; -.
DR   PRIDE; A1TVU0; -.
DR   EnsemblBacteria; ABM35078; ABM35078; Aave_4541.
DR   KEGG; aav:Aave_4541; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; FDTCMVT; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000002596; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..622
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_5000208647"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        337..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   622 AA;  67380 MW;  472A4315E872CA83 CRC64;
     MQRSKSSLAA LTLGAIGVVY GDIGTSVLYA VKEVFGSGHV AFTPQNVYGV LSILFWTLTT
     IVSLKYVVLV LRADNNGEGG LIAMLALASQ AVKDKPRLRS ALLGIGVFGT SLFYGDGVIT
     PAISVLSAVE GLEVVSPHFG KAVIPLTLIV LFCLFAVQKR GTSGIGRYFG PVTLVWFTSI
     AALGVPHIVG HPEILGALSP HHALGFIWRS PGTSFIILGA VVLCVTGAEA LYADLGHFGK
     KPIRLAWFSV AMPALTINYF GQGALLLAEP EAVKNPFYMM APDWALIPLV IMATMATVIA
     SQALITGAFS VTKQVIQLGY LPRLNILHTS VRDTGQIYIP FVNWALFLAI VLAVVMFRSS
     SNLAAAYGIA VTLDMLITTV LTFFVIRYGW RYPLALCIAA TGFFFLVDLA FFGSNLLKLL
     QGGWFPLMIG SIVFMLMMTW KRGRELLNEK LRADAIDLRD FLTAVFVNPP TRVDGTAVFL
     TAEPGAVPNA LLHNLKHNKV LHQQNLFVTV RNHEVPWIGL DKRLQVEALG GDCWQVMVHY
     GFKNDPDLPG ALALMRGRGC ELESMTTSYF LSRDVVTPTI GSGMAPWREK LFAQMHHNAS
     GAAGFLNLPS NSVVELGSKI EI