ID   KUP_ACIBT               Reviewed;         625 AA.
AC   A3M9P9;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 2.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=A1S_3254;
OS   Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC
OS   KC755 / 5377).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=400667;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377;
RX   PubMed=17344419; DOI=10.1101/gad.1510307;
RA   Smith M.G., Gianoulis T.A., Pukatzki S., Mekalanos J.J., Ornston L.N.,
RA   Gerstein M., Snyder M.;
RT   "New insights into Acinetobacter baumannii pathogenesis revealed by high-
RT   density pyrosequencing and transposon mutagenesis.";
RL   Genes Dev. 21:601-614(2007).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000521; ABO13643.2; -; Genomic_DNA.
DR   RefSeq; WP_001181667.1; NZ_CP053098.1.
DR   AlphaFoldDB; A3M9P9; -.
DR   GeneID; 66395562; -.
DR   KEGG; acb:A1S_3254; -.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..625
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000292614"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        340..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   625 AA;  68892 MW;  A2A5ACA315FBD56A CRC64;
     MQNTAKKATL PATALAALGV VFGDIGTSPL YALKESFHAA HGLGIQPENV LGILSIIFWC
     LMLIISIKYV AIVMRADNNG EGGIMALLAL NLRKAKIADN KKIYMIAIGF IGASLFFGDG
     IITPAISVLS AVEGLSIATD VFDPFIMPIA IAIIVTLFLV QKHGTAFVGK FFGPITLVWF
     LSLGILGIHS VIQTPVVLGM FSPHWAIQFI YHHPIMTFFV MGAVVLTVTG GEALYADMGH
     FGPVPIRLAW FFVVLPCLVL NYAGQGALLL RDPAAIENPF YLLVPQWALY PMIIMATMAT
     VIASQAVISG VFSLARQAIQ LGYLPRLSIK HTSESEEGQI YVPFLNWLLL IAIIILILIF
     KTSSNLASAY GLAVTLTMLC DTILVAVFIY SAWKWSLPKV LLLIIPFFIL ESVLVGATSL
     KILSGGWVPL LIGAIAVTIL MTWKRGRELT FAKLEHDTLS LDLFVKSIGN SVHWVPGDAV
     FMTGTPNVVP HAMLHNIKHN KVLHQRNILV TVVIEDVPFV APEERITTET LAEHFFRIKI
     FYGFKDEMNV PKALMQAYEQ LGLEYDLMHI SFFISRDRIV HSVGDGMSPW REKLFISMQR
     NTSPVSDFYQ IPTNRVVELG SQIEI