ID   KUP_ACICJ               Reviewed;         630 AA.
AC   A5FUT7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Acry_0141;
OS   Acidiphilium cryptum (strain JF-5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acidiphilium.
OX   NCBI_TaxID=349163;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JF-5;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Sims D., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Magnuson T., Richardson P.;
RT   "Complete sequence of chromosome of Acidiphilium cryptum JF-5.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000697; ABQ29369.1; -; Genomic_DNA.
DR   RefSeq; WP_007422440.1; NC_009484.1.
DR   AlphaFoldDB; A5FUT7; -.
DR   STRING; 349163.Acry_0141; -.
DR   EnsemblBacteria; ABQ29369; ABQ29369; Acry_0141.
DR   KEGG; acr:Acry_0141; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; FDTCMVT; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000000245; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..630
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000315980"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        374..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        405..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   630 AA;  68445 MW;  E7CFDBD79EDC9143 CRC64;
     MSESATPHGS PGEKLRLAGL IGVLGVVYGD IGTSPLYAVQ ASLSYFPGNK LQESDVLGLL
     SLIFWALIIT VTIKYVLLIM RADNEGEGGT LSLMALAQRV TQSDRTKWII GIIGICGAGL
     FFGDATITPA ISVLSAVEGM EVVSPGLKEF VLPIAIAVIL VLFFVQRFGT ARVGGAFGPI
     MVIWFVVIGA LGLHQIFIHP NVLRALVPVY GAAFIMRHDL LAFIALGSVV LAVTGAEALY
     ADMGHFGAKP IRVSWLFFVL PCLLLNYFGQ GALVIRDPHA ASNPFFFLLP HALVVPMVIL
     ATIATVIASQ AVISGAYSVA RQSTQLGLLP RMPIRYTNET EQGQIYVPPV NSFLFVVVVL
     LVLGFGSSSA LASAYGIAVT GTFLSTNALA AFVYCRHFNW PLRRTVLVFG AIGLVDFAFF
     SSNVLKVFDG GWVPLAIGFS LITVMTTWRR GRALLHQRWQ QDSLPLASFL GRLPQSRIVR
     VPGVAVFMTG NPEYTPSSLL HNLKHNKVLH ETVVFVTVRN PGVPFVGDAR RAKVEELSEG
     VYRVLLSFGF MESPNIPRAL DLLREQGLPF NPMQISYFLG RETIVAATVP KLGFIRRAIF
     LFMLRNAISA TEFFKIPSDR VVELGVRIAI