KUP_ACISJ
ID KUP_ACISJ Reviewed; 622 AA.
AC A1WCP0;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Ajs_3909;
OS Acidovorax sp. (strain JS42).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax; unclassified Acidovorax.
OX NCBI_TaxID=232721;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS42;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.;
RT "Complete sequence of chromosome 1 of Acidovorax sp. JS42.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR EMBL; CP000539; ABM44015.1; -; Genomic_DNA.
DR RefSeq; WP_011806995.1; NC_008782.1.
DR AlphaFoldDB; A1WCP0; -.
DR STRING; 232721.Ajs_3909; -.
DR EnsemblBacteria; ABM44015; ABM44015; Ajs_3909.
DR KEGG; ajs:Ajs_3909; -.
DR eggNOG; COG3158; Bacteria.
DR HOGENOM; CLU_008142_4_2_4; -.
DR OMA; FDTCMVT; -.
DR Proteomes; UP000000645; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01522; Kup; 1.
DR InterPro; IPR003855; K+_transporter.
DR InterPro; IPR023051; K+_uptake_low_affin.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..622
FT /note="Probable potassium transport system protein kup"
FT /id="PRO_5000212251"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 419..439
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ SEQUENCE 622 AA; 67274 MW; 1E011CE0D24C84EC CRC64;
MQTSKSSLAA LTLGAIGVVY GDIGTSVLYA VKEVFGSGHV PFTHANVYGV LSVLFWTLTV
IVSLKYVVLV LRADNHGEGG LIAMLALASQ AVKDRPRLRG WLLGLGIFGT SLFYGDGVIT
PAISVLSAIE GLEVVSPHFG KAVIPLTLVV LFGLFAVQKR GTAGVGRYFG PVTLVWFFTI
AALGVPHIVG HPEILGALSP HHALGFILGN PGISFIILGA VVLCVTGAEA LYADLGHFGK
RPIRLAWFSV AMPALTINYF GQGALLLAEP SAVKNPFYMM APDWALVPLV VLATMATVIA
SQALITGAFS VTKQVIQLGY LPRLNIQHTS VRETGQIYLP FVNWSLFVAI VLAVVMFRNS
SNLAAAYGIA VTLDMLITTV LTFFVIRYGW GYPLALCVAT TGFFFVVDLA FFSSNLLKLL
QGGWFPLMIG GLVFTLMMTW KRGRELLNDK LREDSIGLQD FLASVQANPP MRVDGTAVFL
SAEAGVVPNA LLHNLKHNKV LHRQNLFVTV RYHETPWIGL DQRLQVAPLG GDCWQVTVNY
GFKNELDLPS ALRLMHGRGC ELETMSTSYF LSRDVVVPTI GSGMAPWREK LFAQMHHNAS
GVAAFLHLPS NAVVELGSKV EI