ID   KUP_AERS4               Reviewed;         608 AA.
AC   A4SLX1;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=ASA_1816;
OS   Aeromonas salmonicida (strain A449).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=382245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A449;
RX   PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA   Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA   Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA   Brown L.L.;
RT   "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT   the evolution of a fish pathogen.";
RL   BMC Genomics 9:427-427(2008).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000644; ABO89893.1; -; Genomic_DNA.
DR   RefSeq; WP_005315176.1; NC_009348.1.
DR   AlphaFoldDB; A4SLX1; -.
DR   STRING; 382245.ASA_1816; -.
DR   EnsemblBacteria; ABO89893; ABO89893; ASA_1816.
DR   KEGG; asa:ASA_1816; -.
DR   PATRIC; fig|382245.13.peg.1799; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   OMA; AADQFEI; -.
DR   Proteomes; UP000000225; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
DR   TIGRFAMs; TIGR00794; kup; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..608
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000292615"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        337..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   608 AA;  66608 MW;  F36A6C26EDFD1998 CRC64;
     MSCDNKQALS GVTLAAIGVV YGDIGTSPLY TLRECLSGQF GIRAEPAAIL GFLSLIFWLL
     ILVVSVKYLS FVMRADNAGE GGILTLMSLA TRNASPRWTP VLIILGLIGG SFFYGEVVIT
     PAMSVMSAIE GLSLMAPSLD PYIVPLSVLV LTLLFAIQKH GTAMVGKLFA PIMLTWFLTL
     AVLGLRSIIQ NPEVLGALNP IWALRFFAEY QTTSFFALGA VVLAITGVEA LYADMGHFGK
     NPIRLAWFVV VLPSLVLNYF GQGALLLDNP AAIANPFFLL APKWALLPLL VLATMATVIA
     SQAVISGVFS LTRQAVRLGY LSPIRIVHTS EQESGQIYIP VINWILYISV VIVIMSFEHS
     SNLAAAYGIA VTGTMVLTSI LFCSVAKNSW HWPTYLVAAL FALLLAIDVP LFAANLGKIF
     SGGWLPLTLG AVMFTLMTSW KSERFQLIRR LNEHGNSLEP MIASLEKSPP TRVAGTAVYM
     SRVVNVIPHA LLHNLKHNKV LHERIILLTL RVEDVPYVHN VRRVCIEQLS PTFWRVVASY
     GWRETPNMEE IFHRCNAEGL SCRMMETSFF MAHESLIMKE RPCAANCLCC CSATPCAQRI
     SSRSRPIG