ID   KUP_ANADE               Reviewed;         670 AA.
AC   Q2IPI8;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Adeh_0949;
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R.,
RA   Gilna P., Kiss H., Schmutz J., Larimer F., Land M., Kyrpides N.,
RA   Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S., Kirby J.R.,
RA   Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000251; ABC80724.1; -; Genomic_DNA.
DR   RefSeq; WP_011420007.1; NC_007760.1.
DR   AlphaFoldDB; Q2IPI8; -.
DR   STRING; 290397.Adeh_0949; -.
DR   EnsemblBacteria; ABC80724; ABC80724; Adeh_0949.
DR   KEGG; ade:Adeh_0949; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_7; -.
DR   OMA; AADQFEI; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..670
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279765"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        440..460
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        464..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..29
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  71715 MW;  0A7CAEF359F0B211 CRC64;
     MSQIPSPNDP PPAGAVPTSG APAGPSATPA PSPTAGFSLP EHRPAPTGKA LAALAVGALG
     VVYGDIGTSP LYSLKECFGG PHGVHPTDAN VLGVLSLVFW AMTFVVTFKY MSFVMRADNR
     GEGGILALMA LVGKTETTRL GRRVLLMLGL FGAALLYGDG IITPAISVLG AVEGVAVAAP
     AMERVVVPAT VVILVFLFLF QKQGTAKVGA VFGPIMLVWF ATIAVLGVRG ILHDPSILRA
     LLPTHALSFF ARNGWHGFLV LGGVVLVITG GEALYADMGH FGKRPIRVAW LGLAMPALLL
     NYLGQGALLL HDPGAARNPF YLLAPEWALY PTIAIATAAA IVASQALISG AYSLTQQAIQ
     LGYSPRVTIR HTSQREIGQI YLPEVNWMLG TACVALVLGF QTSSRLASAY GIAVTGTMIV
     TTLLFHRVMR DRWGWARWKA WPLTVLFLTV DASFFLANVV KFRDGGWFPI AAAALVFTLM
     STWKRGRDAL ALMLKDAGLP LDLFMADVAR RKVQRVAGTA VFMTSNPGGV PPVLLHHLKH
     NKVLHERVIL VSILAHEIPF VAEAERVNAR ELGSGFFQVI AHYGFMETPD VPALLDSLPR
     RALAGPRLTI VPMETTYFLG RETLLANGPS TIPTWRKRLF IVMARNAQTA SAFFGLPPNR
     VVEMGAQIQL