KUP_ANADF
ID KUP_ANADF Reviewed; 663 AA.
AC A7H902;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Anae109_0989;
OS Anaeromyxobacter sp. (strain Fw109-5).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter;
OC unclassified Anaeromyxobacter.
OX NCBI_TaxID=404589;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fw109-5;
RX PubMed=25614562; DOI=10.1128/genomea.01449-14;
RA Hwang C., Copeland A., Lucas S., Lapidus A., Barry K., Glavina Del Rio T.,
RA Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.C.,
RA Detter J.C., Han C.S., Schmutz J., Larimer F.W., Land M.L., Hauser L.J.,
RA Kyrpides N., Lykidis A., Richardson P., Belieav A., Sanford R.A.,
RA Loeffler F.E., Fields M.W.;
RT "Complete genome sequence of Anaeromyxobacter sp. Fw109-5, an anaerobic,
RT metal-reducing bacterium isolated from a contaminated subsurface
RT environment.";
RL Genome Announc. 3:0-0(2015).
CC -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR EMBL; CP000769; ABS25198.1; -; Genomic_DNA.
DR RefSeq; WP_011985304.1; NC_009675.1.
DR AlphaFoldDB; A7H902; -.
DR STRING; 404589.Anae109_0989; -.
DR EnsemblBacteria; ABS25198; ABS25198; Anae109_0989.
DR KEGG; afw:Anae109_0989; -.
DR eggNOG; COG3158; Bacteria.
DR HOGENOM; CLU_008142_4_2_7; -.
DR OMA; FDTCMVT; -.
DR OrthoDB; 589903at2; -.
DR Proteomes; UP000006382; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01522; Kup; 1.
DR InterPro; IPR003855; K+_transporter.
DR InterPro; IPR023051; K+_uptake_low_affin.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..663
FT /note="Probable potassium transport system protein kup"
FT /id="PRO_0000315981"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 433..453
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 455..475
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 71322 MW; 040C36FC72160F7A CRC64;
MSDNPSSRAG PEVVPTPPPS PAAEAAVTAL PAHGHRPPAT GSALAKLALG ALGVVYGDIG
TSPLYALKEC FTGHHGVQAT PANVLGVLSL VFWAMTFVVT FKYLSFVMRA DNRGEGGILA
LLALVGKHEV RRSGKQLLII LGLFGAALLY GDGVITPAIS VLGAVEGLSV AAPALEHWVV
PVTVGILALL FFIQRRGTAA VGAVFGPVML VWFLCIAILG VRGILFDATI LQAVLPTHAV
AFFARNSWHG FLVLGGVVLV ITGGEALYAD MGHFGKRPIR FAWLLVAMPA LMLNYMGQGA
ILLHDPQAAR NPFYLLVPGW ALYPMIAVAT AAAIVASQAL ISGAFSLTRQ AVQLGYSPRV
TIRHTSSTEI GQIYVPEVNA LLGAATIALV LGFKSSSNLA AAYGIAVTGT MAITTLLFHR
VARDLWRWPR WRAWPLTLLF LLVDLAFFGA NIVKVEEGGW FPLAAAAFVF TLLSTWKRGR
EGLADLMRGA GLPLDVFLED IARRKPQRVP GTAVFMTGNT GTVPPVLLHH LKHNKVLHER
VVLTSIMSEE IPSVRDAERV TVKELGSGFI QVIARYGFME TPDVPAMFAS LPHRKLDGPR
IELKPMETTY YLGRETLLPT GPSKMARWRK RLFIIMSRNA QTASAFFGLP PNRVVEMGAQ
LQL