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KUP_ANADF
ID   KUP_ANADF               Reviewed;         663 AA.
AC   A7H902;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Anae109_0989;
OS   Anaeromyxobacter sp. (strain Fw109-5).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter;
OC   unclassified Anaeromyxobacter.
OX   NCBI_TaxID=404589;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fw109-5;
RX   PubMed=25614562; DOI=10.1128/genomea.01449-14;
RA   Hwang C., Copeland A., Lucas S., Lapidus A., Barry K., Glavina Del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.C.,
RA   Detter J.C., Han C.S., Schmutz J., Larimer F.W., Land M.L., Hauser L.J.,
RA   Kyrpides N., Lykidis A., Richardson P., Belieav A., Sanford R.A.,
RA   Loeffler F.E., Fields M.W.;
RT   "Complete genome sequence of Anaeromyxobacter sp. Fw109-5, an anaerobic,
RT   metal-reducing bacterium isolated from a contaminated subsurface
RT   environment.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000769; ABS25198.1; -; Genomic_DNA.
DR   RefSeq; WP_011985304.1; NC_009675.1.
DR   AlphaFoldDB; A7H902; -.
DR   STRING; 404589.Anae109_0989; -.
DR   EnsemblBacteria; ABS25198; ABS25198; Anae109_0989.
DR   KEGG; afw:Anae109_0989; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_7; -.
DR   OMA; FDTCMVT; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000006382; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..663
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000315981"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        399..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        433..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        455..475
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   663 AA;  71322 MW;  040C36FC72160F7A CRC64;
     MSDNPSSRAG PEVVPTPPPS PAAEAAVTAL PAHGHRPPAT GSALAKLALG ALGVVYGDIG
     TSPLYALKEC FTGHHGVQAT PANVLGVLSL VFWAMTFVVT FKYLSFVMRA DNRGEGGILA
     LLALVGKHEV RRSGKQLLII LGLFGAALLY GDGVITPAIS VLGAVEGLSV AAPALEHWVV
     PVTVGILALL FFIQRRGTAA VGAVFGPVML VWFLCIAILG VRGILFDATI LQAVLPTHAV
     AFFARNSWHG FLVLGGVVLV ITGGEALYAD MGHFGKRPIR FAWLLVAMPA LMLNYMGQGA
     ILLHDPQAAR NPFYLLVPGW ALYPMIAVAT AAAIVASQAL ISGAFSLTRQ AVQLGYSPRV
     TIRHTSSTEI GQIYVPEVNA LLGAATIALV LGFKSSSNLA AAYGIAVTGT MAITTLLFHR
     VARDLWRWPR WRAWPLTLLF LLVDLAFFGA NIVKVEEGGW FPLAAAAFVF TLLSTWKRGR
     EGLADLMRGA GLPLDVFLED IARRKPQRVP GTAVFMTGNT GTVPPVLLHH LKHNKVLHER
     VVLTSIMSEE IPSVRDAERV TVKELGSGFI QVIARYGFME TPDVPAMFAS LPHRKLDGPR
     IELKPMETTY YLGRETLLPT GPSKMARWRK RLFIIMSRNA QTASAFFGLP PNRVVEMGAQ
     LQL
 
 
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