ID   KUP_AROAE               Reviewed;         640 AA.
AC   Q5P3E3;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=AZOSEA20460;
GN   ORFNames=ebA3621;
OS   Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Aromatoleum.
OX   NCBI_TaxID=76114;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EbN1;
RX   PubMed=15551059; DOI=10.1007/s00203-004-0742-9;
RA   Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F.,
RA   Reinhardt R.;
RT   "The genome sequence of an anaerobic aromatic-degrading denitrifying
RT   bacterium, strain EbN1.";
RL   Arch. Microbiol. 183:27-36(2005).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CR555306; CAI08171.1; -; Genomic_DNA.
DR   RefSeq; WP_011237864.1; NC_006513.1.
DR   AlphaFoldDB; Q5P3E3; -.
DR   STRING; 76114.ebA3621; -.
DR   PRIDE; Q5P3E3; -.
DR   EnsemblBacteria; CAI08171; CAI08171; ebA3621.
DR   KEGG; eba:ebA3621; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; GHETIIP; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000006552; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..640
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000208991"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        265..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        297..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        384..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        437..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   640 AA;  69484 MW;  EC942E5076F0BDF0 CRC64;
     MQALEGVNTS PAAAAAAHAP APRRGIAGLA VAAVGVVYGD IGTSPLYTLK EVFNGPHAVP
     VTPQNVYGIL SLVFWALVLV VSAKYVLFIT RADNRGEGGI MALTSLVLRA VPPGRKAWVL
     SALGVFGAAL FYGDGMITPA ISVLSAVEGL EVATPAFRPY VLPIALAVLC GLFVIQRHGT
     GSVGRIFGPV MLVWFVLLAV LGIAGITLHP EIIGALDPRW ALRFFADMPL VGWLSLGAVV
     LAITGGEALY ADMGHFGRRP IKFAWFLVVF PSLYLNYLGQ GALILDHPDN VRNPFYLLVP
     DALVYPMVAM ATLATIIASQ AVISGAYSLT RQAMQLGYAP RMRTIFTSER EMGQIYVPSI
     NWMLLGAVVA LVVGFRSSSA LASAYGIAVT LTMMIDTLLA FVVVRALWGW GRLQAGLFLG
     VFLAVDVAFF SATTVKILAG GWFPLLVGAL IFTLLTTWKR GRELLNRRLR TDTIPLDTFI
     RSMFNSPSPR VDGTAVFLTT WLEGVPRALL HNLVHNKVLH HRVVLLTVET ADVPHVPDSE
     RVAVEELDYG FYRVRVNYGF KDDPDLPAAL VRCADFGLKF AMMETSFFLG RETLVSRVGS
     GMPRWREKLF IVMFRNAGSA ADYFHIPPNR VVELGTQVEL