ID   KUP_BIFAA               Reviewed;         649 AA.
AC   A1A3M0;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=BAD_1522;
OS   Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 /
OS   E194a).
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=367928;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15703 / DSM 20083 / NCTC 11814 / E194a;
RA   Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S.,
RA   Tanaka K., Watanabe K.;
RT   "Bifidobacterium adolescentis complete genome sequence.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01522};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF40303.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AP009256; BAF40303.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; A1A3M0; -.
DR   STRING; 1680.BADO_1489; -.
DR   EnsemblBacteria; BAF40303; BAF40303; BAD_1522.
DR   KEGG; bad:BAD_1522; -.
DR   HOGENOM; CLU_008142_4_1_11; -.
DR   Proteomes; UP000008702; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..649
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000292616"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        195..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        364..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   649 AA;  72281 MW;  806D45587D9ACC0B CRC64;
     MAIVALGVVY GDIGTSPLYT MQTFLNGQGG LAHTDRAAVL GILSLVFWSI TLITTVKYVF
     IAMRIDNNGE GGIFALYSLI RKYGAWLAIP AMLGGAAFLA DSVLTPAVSI SSAVEGLETL
     PLLEPIMSGN KELTLMITIV IIVCLFAVQS RGTERIGRTF GTVVMIWFSF LAVVGLVNLS
     SDWSVLEALN PVYGVEFLFS HHNAAGLAVM GTVFLSTTGA EALYSDMGHV GRGNIYFTWP
     FIKIALVFCY FGQGAWMLNH WDDTAYNHMH GLNPFFEMMT PSVRYVAVLL SVCAGVIASQ
     ALITGAYTMV SEATRLNWMP HLQVRYPART RGQLYIPVVN AVLCVSTLLV LAMFRDSEHI
     SAAYGLALTV TMITTTILLA VYIWHDGKRV GAVVFTVVFL AIQFLFFFAS MAKFLHGGWF
     TMLLTLAILL IMYTWNEGTK LERAQRRHMQ PADCVPVLKR LHEDDSIPYF ADNIVYLTSD
     PEMKRVDTDI FFSIFADHPK RARAWWAVSV ETSDNPFTRE YSVENFGTDF LFRVRIRLGF
     KVSQSIPAYI HQIMNDLSKS GDLPKQTTRY PKLDADPNIG PIRYVLIHKA LMPESKVSQK
     GAISLQIKYA IRHLAGSPVK WFGLAPYNPL IEIQPLFLAT ERPPRLKRV