ID   KUP_BORA1               Reviewed;         626 AA.
AC   Q2KZC5;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=BAV2115;
OS   Bordetella avium (strain 197N).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=360910;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=197N;
RX   PubMed=16885469; DOI=10.1128/jb.01927-05;
RA   Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D.,
RA   Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A.,
RA   Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J.,
RA   Parkhill J., Temple L.M.;
RT   "Comparison of the genome sequence of the poultry pathogen Bordetella avium
RT   with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals
RT   extensive diversity in surface structures associated with host
RT   interaction.";
RL   J. Bacteriol. 188:6002-6015(2006).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; AM167904; CAJ49725.1; -; Genomic_DNA.
DR   RefSeq; WP_012417781.1; NC_010645.1.
DR   AlphaFoldDB; Q2KZC5; -.
DR   STRING; 360910.BAV2115; -.
DR   EnsemblBacteria; CAJ49725; CAJ49725; BAV2115.
DR   GeneID; 41393950; -.
DR   KEGG; bav:BAV2115; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000001977; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..626
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279767"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        288..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        367..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        399..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        421..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   626 AA;  68821 MW;  1610F8C0033B908C CRC64;
     MSHTSEQGAS RPVALMMGAL GVVYGDIGTS PLYTLRACLT EFADLQPAHI LGVLSILFWL
     LMVVVSFKYV LLILRADNQG EGGTLALLEL AVRGRSGRLR TFFVVLGIFG AALFYGDSMI
     TPAISVLSAI EGIGVVSHTL DPWIVPLALL VLLALFAIQS RGTGTVGKLF GPVMVVWFAT
     LGVLGGWQVW QTPEVLVALN PIWALRFVFE FPVMSFLLLG AVVLALTGAE ALYADMGHFG
     RPAIRRAWFS MVLPSLTLCY LGQGALLLRD PSAIRNPFFL MAPEWGLAAL VGLATVATVV
     ASQAVISGAF SVTRQAVQLG FWPRMQILHT SAVEKGQIYL PQVNALLLCA VLVLVITFRN
     SENLAAAYGF AVTGTMLMTS ILAFAVLPRG STGAKRLGWM LVLGVLLIID VLLFSANIFK
     IHEGGWMPLL VGVVVFTLMM TWRRGRQLLA DIQARDRQPL QEFMDQLESY PPARVPGTAV
     FMTLNNDNVP PALLHNLKHN KVLHDHVLFL SIRVADVPYI AEQDRFSVKR VSASSWQAVI
     HYGFKEDPDV PEALRLVAEA YPEIDLEPMR TSFFLSRQAV VAARRPAMSR WRRTVFSFMA
     RNSTRSTKFF KIPPNRVVEM GMQIEL