ID   KUP_BURCH               Reviewed;         638 AA.
AC   A0K7S3;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   OrderedLocusNames=Bcen2424_1799;
OS   Burkholderia cenocepacia (strain HI2424).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=331272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI2424;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., LiPuma J.J., Gonzalez C.F.,
RA   Konstantinidis K., Tiedje J.M., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000458; ABK08550.1; -; Genomic_DNA.
DR   RefSeq; WP_006478689.1; NC_008542.1.
DR   AlphaFoldDB; A0K7S3; -.
DR   KEGG; bch:Bcen2424_1799; -.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..638
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279770"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        304..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        352..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        382..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        434..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   638 AA;  69145 MW;  BB47E55137038AA5 CRC64;
     MNDTTHATDA AHSPHSTQQH SMRALAIAAI GVVFGDIGTS PLYSLKEAFS PAHGIPLTEG
     SILGVISLLF WAILLVVGVK YLLFVMRADN NGEGGVLALM ALSLRPLDSK TRVAGALMAL
     GIFGACMFYG DAVITPAISV MSAVEGLEIA TPHLSHLVLP ITIVILIALF WIQRHGTALV
     GKLFGPIMVL WFVVIAALGV YHIVRVPGII AAINPYYAAS FMADHLLQAY VVLGSVVLVL
     TGAEALYADM GHFGAKPIRY AAYGLVMPSL VLNYFGQGAL LIQNPKAIEN PFFLLAPEWG
     LLPLVVLSTV ATVIASQAVI SGAYSLTSQA IQLGYVPRMK VLHTSELAIG QIYVPVVNWL
     LLAVILCIVV GFKSSDNLAA AYGIAVTATM VITTVLACVV MVKVWNWNRL LVGAIIAVFL
     AIDLGFFGAN LLKVAQGGWL PLGIGALLFF LLMTWYKGRH IVKERTAADG IPLEPFLQGL
     LAHPPHRVSG TAIYLTGNDK LVPVSLLHNL KHNKVLHERT IFLTFVTRDI PYVRDDKRQS
     ARDAGGGLYI VKAEYGFNET PDVKAVLEEF GRTHDMTFEL MDTSFFLARE TVVPTHLPGM
     SIWRERVFAW MHQNAAKPTD FFAIPANRVV ELGTKIEI