ID   KUP_BURL3               Reviewed;         638 AA.
AC   Q39FS2;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   OrderedLocusNames=Bcep18194_A5100;
OS   Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 /
OS   R18194 / 383).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=482957;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia sp. 383.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000151; ABB08694.1; -; Genomic_DNA.
DR   RefSeq; WP_011352250.1; NC_007510.1.
DR   AlphaFoldDB; Q39FS2; -.
DR   EnsemblBacteria; ABB08694; ABB08694; Bcep18194_A5100.
DR   GeneID; 45094976; -.
DR   KEGG; bur:Bcep18194_A5100; -.
DR   PATRIC; fig|482957.22.peg.2037; -.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000002705; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..638
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279773"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        304..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        352..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        382..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        434..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   638 AA;  69227 MW;  DA4FD990AA1A397A CRC64;
     MNDTIHATDA AHAPHSTQQH SMRALAIAAI GVVFGDIGTS PLYSLKEAFS PAHGIPLTEG
     SILGVISLLF WAIILVVGIK YLLFVMRADN NGEGGVLALM ALSLRPLDSK TRVAGALMAL
     GIFGACMFYG DAVITPAISV MSAVEGLEIA TPHLSHLVLP ITIVILIALF WIQRHGTALV
     GKLFGPIMVL WFVAIAALGV YHIVRVPGIM AAINPYYAAS FMADHLLQAY VVLGSVVLVL
     TGAEALYADM GHFGAKPIRI AAYGLVMPSL VLNYFGQGAL LIQNPKAIEN PFFLLAPEWG
     LLPLVILSTV ATVIASQAVI SGAYSLTSQA IQLGYVPRMK VLHTSELAIG QIYVPVVNWL
     LLFVILCIVI GFKSSDNLAA AYGIAVTATM VITTVLAAVV MVKVWNWNRL LVGAIIAVFL
     AVDLGFFGAN LLKVAQGGWL PLGIGALLFF LLMTWYKGRH IVKERTAADG IPLEPFLQGL
     LAHPPHRVSG TAIYLTGNDK LVPVSLLHNL KHNKVLHERT IFLTFVTRDI PYVRDDKRQT
     SRDAGGGLYI VRAEYGFNET PDVKAVLEEF GRTHDMTFEL MDTSFFLARE TVVPTHLPGM
     SIWRERVFAW MHQNAAKPTD FFSIPANRVV ELGTKIEI