KUP_BURTA
ID KUP_BURTA Reviewed; 630 AA.
AC Q2SWD1;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-MAR-2007, sequence version 2.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=BTH_I2247;
OS Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS E264).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=271848;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA DeShazer D.;
RT "Bacterial genome adaptation to niches: divergence of the potential
RT virulence genes in three Burkholderia species of different survival
RT strategies.";
RL BMC Genomics 6:174-174(2005).
CC -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC {ECO:0000255|HAMAP-Rule:MF_01522}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABC36940.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000086; ABC36940.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_009890848.1; NZ_CP008785.1.
DR AlphaFoldDB; Q2SWD1; -.
DR PRIDE; Q2SWD1; -.
DR EnsemblBacteria; ABC36940; ABC36940; BTH_I2247.
DR KEGG; bte:BTH_I2247; -.
DR HOGENOM; CLU_008142_4_2_4; -.
DR OrthoDB; 589903at2; -.
DR Proteomes; UP000001930; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01522; Kup; 1.
DR InterPro; IPR003855; K+_transporter.
DR InterPro; IPR023051; K+_uptake_low_affin.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..630
FT /note="Probable potassium transport system protein kup"
FT /id="PRO_0000279774"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ SEQUENCE 630 AA; 68573 MW; 8ACF6FFA4AE40C3F CRC64;
MTDTNHSSMR QHSLQSLAIA AIGVVFGDIG TSPLYSLKEA FSPAHGIPLT PSAILGVISL
LFWAIILVVG IKYVLFVMRA DNNGEGGVLA LMALSLRPLN PKSRITGLMM ALGIFGACMF
YGDAVITPAI SVMSAVEGLE VATPQLSHLV LPITIVILIA LFWIQRHGTA TVGKLFGPIM
VIWFVTIAAL GVYHIARAPM IVSAINPYYA FSFMSEHVLL AYVVLGSVVL VLTGAEALYA
DMGHFGAKPI RLAAYVLVMP SLVLNYFGQG ALLLLDPKAI ENPFFLLAPQ WAALPLVVLS
TVATVIASQA VISGAYSLTS QAIQLGYVPR MKILHTSELA IGQIYVPVVN WLLLFVILCI
VIGFKSSDNL AAAYGIAVTA TMVITTILAA VVMVKVWNWN KLLVAMIIGV FLVIDLGFFG
ANLLKVEQGG WLPLGIGALL FFLLMTWYKG RHIVKERTAA DGIPLAPFLQ GLLAHPPHRV
SGTAIYLTGN DTLVPVSLLH NLKHNKVLHE RTIFMTFVTR DIPYVKDDER VTVHDAGEGL
YIVKAEYGFN ETPDVKAVLE EVSCQRAMTF ELMDTSFFLA RETVVPTHLP GMSIWRERVF
AWMHQNAAKP TDFFAIPANR VVELGTKIEI