KUP_CAUVC
ID KUP_CAUVC Reviewed; 665 AA.
AC Q9ABT9;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2004, sequence version 2.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=CC_0131;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC {ECO:0000255|HAMAP-Rule:MF_01522}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK22118.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE005673; AAK22118.1; ALT_INIT; Genomic_DNA.
DR PIR; B87265; B87265.
DR RefSeq; NP_418950.1; NC_002696.2.
DR RefSeq; WP_012639885.1; NC_002696.2.
DR AlphaFoldDB; Q9ABT9; -.
DR STRING; 190650.CC_0131; -.
DR EnsemblBacteria; AAK22118; AAK22118; CC_0131.
DR KEGG; ccr:CC_0131; -.
DR PATRIC; fig|190650.5.peg.128; -.
DR eggNOG; COG3158; Bacteria.
DR HOGENOM; CLU_008142_4_2_5; -.
DR OMA; AADQFEI; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01522; Kup; 1.
DR InterPro; IPR003855; K+_transporter.
DR InterPro; IPR023051; K+_uptake_low_affin.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..665
FT /note="Probable potassium transport system protein kup"
FT /id="PRO_0000209006"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 409..429
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 435..455
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 462..482
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 71548 MW; F86362DF60AECB18 CRC64;
MASEAPHASA PDCAPASSDI PQQDGGSTNG HGHDLKGHGF FALALGSVGV VFGDIGTSPL
YAFKEALAAA SHDGVTRSEI FGVVSLALWA LILIVTIKYV VFIMRADNKG EGGVLSLMAL
AQHAMGKRTT LVFVLGVAGA ALFYGDAVIT PAMSVLSAVE GLRTIPALEH GVTNEVVLLI
ATVMLLGLFF IQSRGTASVG KLFGPVCAVW FGVMFSLGLM NLAANPGILM AISPYYAVEF
LAEHGLTGFI VLGAVFLTVT GVEALTADMG HFGRWPIQAA WLFFVLPCLA MNYLGQGAFA
LTTLETAQAA GKAMPELNWF FEMAPEALRL PLVLLAGAAT VIASQAVITG AFSLTQQAIQ
LGLLPRLDVR RTSETQSGQI FVPQLNTMLL LGVLAIMFTF QTSSALAHAY GLAVTGTMIV
TTCMAFIVMR KLWKWSMPMA LLFLVPFLAL DITFLSANAL RFFSGGWLPV LIGAALFTIM
ATWVRGSQIL TDKTRRDSLP VADLMDILRA RAPHRAPGTA IFLTSDPDMT PVALMHNLKH
NKVLHERNVI LTVRTAETPR VSEEERVKIE KVNDDFKKVV VNYGFMESPN IPKALAVCRK
QGLKFDIMAT SFFLGRRSIV PSANSGMPLW QDRLFIYLMR NAANPTDFFK IPPGRVVELG
AQVTV