ID   KUP_CORGB               Reviewed;         628 AA.
AC   A4QC57;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=cgR_0832;
OS   Corynebacterium glutamicum (strain R).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=340322;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R;
RX   PubMed=17379713; DOI=10.1099/mic.0.2006/003657-0;
RA   Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M.,
RA   Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.;
RT   "Comparative analysis of the Corynebacterium glutamicum group and complete
RT   genome sequence of strain R.";
RL   Microbiology 153:1042-1058(2007).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01522};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; AP009044; BAF53804.1; -; Genomic_DNA.
DR   RefSeq; WP_011896886.1; NC_009342.1.
DR   AlphaFoldDB; A4QC57; -.
DR   EnsemblBacteria; BAF53804; BAF53804; cgR_0832.
DR   KEGG; cgt:cgR_0832; -.
DR   HOGENOM; CLU_008142_4_2_11; -.
DR   OMA; AADQFEI; -.
DR   PhylomeDB; A4QC57; -.
DR   Proteomes; UP000006698; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..628
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000296766"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        256..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        346..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        375..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        398..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   628 AA;  69008 MW;  964D8B48A6931426 CRC64;
     MLNRMKSARP KSVAPKSGQA LLTLGALGVV FGDIGTSPLY SLHTAFSMQH NKVEVTPENV
     YGIISMVLWT ITLIVTVKYV MLVTRADNQG QGGILALVAL LKNRGHWGKF VAVAGMLGAA
     LFYGDVVITP AISVLSATEG LTVISPSFER FILPISLAVL IAIFAIQPLG TEKVGKAFGP
     IMLLWFVTLA GLGIPQIIVH PEILQSLSPH WALGLIVAEP FQAFVLLGAV VLTVTGAEAL
     YADMGHFGAR PIRVAWFCVV MPALILTYLG QGALVINQPE AVRNPMFYLA PEGLRIPLVI
     LATIATVIAS QAVISGAYSL TKQAVNLKLL PRMVIRHTSR KEEGQIYMPL VNGLLFVSVM
     VVVLVFRSSE SLASAYGLAV TGTLVLVSVL YLIYVHTTWW KTALFIVFIG IPEVLLFASN
     TTKIHDGGWL PLLTAAVLIV VMRTWEWGSD RVNQERAELE LPMDKFLEKL DQPHNIGLRK
     VAEVAVFPHG TSDTVPLSLV RCVKDLKLLY REIVIVRIVQ EHVPHVPPAE RAEMEVLHHA
     PIRVVRVDLH LGYFDEQNLP ENLHAIDPTW DNATYFLSAL TLRSRLPGKI AGWRDRLYLS
     MERNQASRTE SFKLQPSKTI TVGTELHL