ID   KUP_CUPPJ               Reviewed;         636 AA.
AC   Q472H9;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Reut_A1334;
OS   Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator
OS   (strain JMP 134)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JMP134 / LMG 1197;
RX   PubMed=20339589; DOI=10.1371/journal.pone.0009729;
RA   Lykidis A., Perez-Pantoja D., Ledger T., Mavromatis K., Anderson I.J.,
RA   Ivanova N.N., Hooper S.D., Lapidus A., Lucas S., Gonzalez B.,
RA   Kyrpides N.C.;
RT   "The complete multipartite genome sequence of Cupriavidus necator JMP134, a
RT   versatile pollutant degrader.";
RL   PLoS ONE 5:E9729-E9729(2010).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000090; AAZ60704.1; -; Genomic_DNA.
DR   RefSeq; WP_011297504.1; NC_007347.1.
DR   AlphaFoldDB; Q472H9; -.
DR   STRING; 264198.Reut_A1334; -.
DR   EnsemblBacteria; AAZ60704; AAZ60704; Reut_A1334.
DR   KEGG; reu:Reut_A1334; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..636
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279816"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        350..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        379..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        432..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   636 AA;  69682 MW;  D0B3BB7F82E15015 CRC64;
     MTTQSATTAT SHYFVENPST RALVIGAIGV VFGDIGTSPL YSLKECFSKE HGIPFSPDAV
     LGIISLLFWA MTIVVSIKYV VFVMRADNNG EGGVLALMAL VLRTAAPRSR WAKVLMMLGI
     FGACMFYGDA VITPAISVLS AVEGLEIATP QLSRFVIPIT LVILVALFLI QRNGTSVVGK
     LFGPVMVVWF VTLGLLGLYN LVQAPEILKA FNPYYGISFL IAHSLQAFIV LGSVFLVLTG
     AEALYVDMGH FGARPIRYGW FVLVMPCLIL NYFGQGAMLL TNPAGAENPF YLMVPEPLLI
     PMVVLATCAT VIASQAVISG AFSLTSQAIQ LGFVPRMRVR YTSAAEIGQI YLPVINWILL
     VLVVAVVISF KKSENLAAAY GIAVTTTMVI TTFLAAVVMR NVWKWNPALV TLLGLSFLLV
     DLAFFAANLL KVAEGGWFPL LLGSTAFFLL MTWYSGRKLL RARSLEDGIP LEPFIAGLLA
     HPPHRVEGTA VFLTGNTESV PVSLLHNLKH NRVLHERVVF LSFVTRDIPY VDDEQRLSCK
     DLGGGVFILK SDYGFKETPD VHKVLDLAQR KLGMHFELME TSFFIARESV IPSKLPGMSM
     WRESLFAWMH QNGAKPSDFF QIPANRVVEL GTKVEI