ID   KUP_CYTH3               Reviewed;         655 AA.
AC   Q11PK1;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=CHU_3426;
OS   Cytophaga hutchinsonii (strain ATCC 33406 / DSM 1761 / CIP 103989 / NBRC
OS   15051 / NCIMB 9469 / D465).
OC   Bacteria; Bacteroidetes; Cytophagia; Cytophagales; Cytophagaceae;
OC   Cytophaga.
OX   NCBI_TaxID=269798;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33406 / DSM 1761 / CIP 103989 / NBRC 15051 / NCIMB 9469 / D465;
RX   PubMed=17400776; DOI=10.1128/aem.00225-07;
RA   Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C., Gilna P.,
RA   Han C.S., Lucas S., Misra M., Myers G.L., Richardson P., Tapia R.,
RA   Thayer N., Thompson L.S., Brettin T.S., Henrissat B., Wilson D.B.,
RA   McBride M.J.;
RT   "Genome sequence of the cellulolytic gliding bacterium Cytophaga
RT   hutchinsonii.";
RL   Appl. Environ. Microbiol. 73:3536-3546(2007).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000383; ABG60662.1; -; Genomic_DNA.
DR   RefSeq; WP_011586769.1; NZ_FPJX01000019.1.
DR   AlphaFoldDB; Q11PK1; -.
DR   STRING; 269798.CHU_3426; -.
DR   PRIDE; Q11PK1; -.
DR   EnsemblBacteria; ABG60662; ABG60662; CHU_3426.
DR   KEGG; chu:CHU_3426; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_1_10; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000001822; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..655
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279780"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        53..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        420..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   655 AA;  74077 MW;  80EB11EE4FC6B8B2 CRC64;
     MSTIADSKNH GHQKLTAAGL LISLGIIYGD IGTSPLYVMK AIAGGNVISE NLILGGLSCV
     FWTITLQTTI KYVIITLRAD NKGEGGIFSL FALIRRRNPN LVWPAMIGGA AMLADGIITP
     PISVSSAVEG LLIFNKDIPT IPIVLAIIVM LFMIQRFGTN IVGKFFGPIM FIWFAMLATL
     GLSQLMGNFY VLKAINPMYA FNLLTQYTTV DDKSGFWLLG AVFLCTTGAE ALYSDLGHCG
     RPNIRISWIF VKLALLINYF GQGAWILQNK GYVIKGNPFF GIMPEWFIVY GIIIATMAAI
     IASQAMISGS YTLISEALRL NLWPKVRVKY PSVKKGQLFI PSINLLLLAG CIFVVLWFGE
     SSAMEGAYGL AINITFLMTT ILLAYYLLII KRISFIWVGL LILMYLIIEV SFLVANLEKF
     FHGGYFTLIS SGILAFIMII WYTAHRIKRR LTEYVKIQDY FPLIKELSED TSIPKYSTHL
     IYLTGADNYT QIESKVIYSI FQKQPKRADI YWFLHIDVVD EPYTMEYKVR TMLADDVIRI
     DFKLGFRVEH RINLFFRKVV EDMVNNKEVD FTSRYTSLNK RNVIGDFRFV VLEKHLSNDN
     DLSVMEQFAM DWYFFLKHIS ISESSAFGLD TSSVTVEKVP MVISPMEAFQ LKRVY