ID   KUP_GLUOX               Reviewed;         675 AA.
AC   Q5FQL0;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=GOX1595;
OS   Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Gluconobacter.
OX   NCBI_TaxID=290633;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=621H;
RX   PubMed=15665824; DOI=10.1038/nbt1062;
RA   Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F.,
RA   Ehrenreich A., Gottschalk G., Deppenmeier U.;
RT   "Complete genome sequence of the acetic acid bacterium Gluconobacter
RT   oxydans.";
RL   Nat. Biotechnol. 23:195-200(2005).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000009; AAW61336.1; -; Genomic_DNA.
DR   RefSeq; WP_011253119.1; NZ_LT900338.1.
DR   AlphaFoldDB; Q5FQL0; -.
DR   STRING; 290633.GOX1595; -.
DR   EnsemblBacteria; AAW61336; AAW61336; GOX1595.
DR   KEGG; gox:GOX1595; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; FDTCMVT; -.
DR   Proteomes; UP000006375; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..675
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000209019"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        195..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        222..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        332..352
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        450..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        472..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   675 AA;  73466 MW;  EFDE87282C3BE781 CRC64;
     MEPAMPEHDG DHASNPPHGV GIPNDSAGIV QTIEQARSEG HTHEIGGGEE GSGHERPAGM
     GALLAVLGVV YGDIGTSPLY ALQSSVSIVS SPKAPAQPWE IMGLASLTFW ALMLIVTIKY
     VILIMRADHD GEGGIIALMS LAQRVCKSQH FRWLFGLVGI AGTCLFFGDS IITPAISVLS
     AVEGIETSVP SASHIIIPLA MVVLVALFSV QVLGTGKIGK AFGPIMVCWF SVLAILGIKG
     IFLYPHILLA LSPTFALEFI VLHGYLSFIA LGSVVLSVTG AEALYADMGH FGRAPIRKAW
     LFFVLPSLTL NYFGQAALLI RDPHALSNPF YLLVPHWAQI PMLVLATFAT VIASQAGISG
     SFSLCRQLIQ LGYLPRTRIM HTNASEEAQI YLPSLNWILA FGALVLVLAF RTSSALAAAY
     GIAVTGTFLC TCVLAMVVFR RVFKWKSATV AIVFGFFFIV DSIFFSANVL KIPDGGWVPL
     AIGIISTIIM TTWKRGRSLI AARQQADSMP MGSFLARLPQ SRTIRVPGLA VFLTANPDIV
     PNSLLHNLKH NKVLHDHILF VTVENLDQPE AERGHRAIVQ ELAPNIHRVI VRYGFMEMPN
     LPRALLELNA LGVAFDAIQA SYFTSHELVV RSRVPKMQLW RMWIFLFLLR NAASTTEFLR
     IPPDRVVEFG VRIAI