ID   KUP_GRABC               Reviewed;         640 AA.
AC   Q0BPL2;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   OrderedLocusNames=GbCGDNIH1_2342;
OS   Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Granulibacter.
OX   NCBI_TaxID=391165;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1260 / CGDNIH1;
RX   PubMed=17827295; DOI=10.1128/jb.00793-07;
RA   Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E.,
RA   Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M.;
RT   "Genome sequence analysis of the emerging human pathogenic acetic acid
RT   bacterium Granulibacter bethesdensis.";
RL   J. Bacteriol. 189:8727-8736(2007).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABI63240.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000394; ABI63240.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_025287624.1; NC_008343.2.
DR   AlphaFoldDB; Q0BPL2; -.
DR   STRING; 391165.GbCGDNIH1_2342; -.
DR   EnsemblBacteria; ABI63240; ABI63240; GbCGDNIH1_2342.
DR   KEGG; gbe:GbCGDNIH1_2342; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   Proteomes; UP000001963; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..640
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279788"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        265..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        384..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        440..460
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   640 AA;  70192 MW;  F9A5A3394EFA3BFF CRC64;
     MSAAEKLAAD EKKPIGQPTG QPTGLVMLLG ALGVVFGDIG TSPLYAFKAA LLHFQDDGSV
     INRLEVYGVL SMVFWSLVLI VTVKYVLLVM RADNQGEGGI LSLMALAQRV ANPGRMRYWL
     GMTGIIGACL FFGDGVITPA ISVLSAVEGL EITYPAMKDY VLPIASVVIV ALFMVQWRGT
     SIMGRVFGPI MAVWFLLIGL LGLLAILHHP KVLLALSPGY AGLLLIQHRL LAFIVLGSVV
     LAVTGAEALY ADMGHFGGRP IKQAWLWIVL PALTLNYFGQ GALILHDIKA LDNPFFLLTP
     HWLRLPMVLL ATAATVIASQ AMISGAFSMA RQCVQLGFLP RMTVRHTSET EQGQIYVPQV
     NSALLIGVLA LVLTFRTSDN LAAAYGIAVT GTFLCTGILA VVVFRRQFGW SRRSVMVVFG
     FFFLLDSLFF ASNMLKIPQG GYVPLVLGGL LMAMMTSWSA GRRLLMSRWR QDSLPLASFL
     ARLPQSRILR VPGTAVFLTG NPDYVPGALL HNLKHNKVLH ERVLFLTVKT LDQPEAGPDQ
     HLEVEELAEN VYRVIIRYGF KESPNIPRDL DALRARGVPV ESMQVSYFFG RETIVAGKAP
     KMPLWRLWLF LVMARNAVPA TEFFRIPSDR VVELGVRVPI