ID   KUP_HERAR               Reviewed;         625 AA.
AC   A4GA77;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 2.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=HEAR3308;
OS   Herminiimonas arsenicoxydans.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Herminiimonas.
OX   NCBI_TaxID=204773;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ULPAs1;
RX   PubMed=17432936; DOI=10.1371/journal.pgen.0030053;
RA   Muller D., Medigue C., Koechler S., Barbe V., Barakat M., Talla E.,
RA   Bonnefoy V., Krin E., Arsene-Ploetze F., Carapito C., Chandler M.,
RA   Cournoyer B., Cruveiller S., Dossat C., Duval S., Heymann M., Leize E.,
RA   Lieutaud A., Lievremont D., Makita Y., Mangenot S., Nitschke W., Ortet P.,
RA   Perdrial N., Schoepp B., Siguier P., Simeonova D.D., Rouy Z., Segurens B.,
RA   Turlin E., Vallenet D., van Dorsselaer A., Weiss S., Weissenbach J.,
RA   Lett M.-C., Danchin A., Bertin P.N.;
RT   "A tale of two oxidation states: bacterial colonization of arsenic-rich
RT   environments.";
RL   PLoS Genet. 3:518-530(2007).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CU207211; CAL63414.2; -; Genomic_DNA.
DR   RefSeq; WP_041322848.1; NC_009138.1.
DR   AlphaFoldDB; A4GA77; -.
DR   STRING; 204773.HEAR3308; -.
DR   EnsemblBacteria; CAL63414; CAL63414; HEAR3308.
DR   KEGG; har:HEAR3308; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000006697; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..625
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000296767"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        340..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        397..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   625 AA;  68276 MW;  9AFAAFC356FC03A2 CRC64;
     MASPDKKSSL AALTLAAVGI VYGDIGTSPL YTMKEVFSKE HGLDLTPENL LGVVSLIVWG
     LIIIVSLKYV TLVLRANNRG EGGIMALMAL ALSSVTKNSR WYFPLMVMGL FGATLFYGDS
     VITPAISVLS AVEGLGVATS AFDPYVVPVT VAILVGLYSL QARGTAGIGK WFGPVMLIWF
     ITLAVMGVVN IIDAPYILHA LNPWHALHFL SGNGFLAFIA LGAVVLAFTG AEALYADMGH
     FGAKPIRMAW FLIAFPALSL NYLGQGALLL LNPEAVTNPF YQQLGAWSIY PLVALSTMAA
     IIASQATISG TFSMTKQAIA LGFLPRMKIE FTSASQIGQI YIPAVNWLQM IVVVLAVIGF
     GSSSNLAAAY GIAVTATMMV TTVLTFFVIR YRWKYNLILC VAATGFFLVI DLSLFSANML
     KLFHGGWFPL LLGVVLFTLM LTWKRGRELV FENLQKHAIP LEDFLASLFI SPPTRVPGTA
     IFLRGESDGV PHAMLHNLSH NKVLHERVVF LTVRMMEVPY VPKADQVRIE HLGDDCYQMN
     VTYGFKNVPD IPAALDLAKE QGLEFEMMET SFFIARQTVV ANPVRGMALW REHIFVAMSR
     HARGAADYYQ IPSNRVIELG TKVEI