ID   KUP_LATSS               Reviewed;         680 AA.
AC   Q38WG4;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=LCA_1166;
OS   Latilactobacillus sakei subsp. sakei (strain 23K) (Lactobacillus sakei
OS   subsp. sakei).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Latilactobacillus.
OX   NCBI_TaxID=314315;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=23K;
RX   PubMed=16273110; DOI=10.1038/nbt1160;
RA   Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M.,
RA   Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V.,
RA   Zagorec M.;
RT   "The complete genome sequence of the meat-borne lactic acid bacterium
RT   Lactobacillus sakei 23K.";
RL   Nat. Biotechnol. 23:1527-1533(2005).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01522};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CR936503; CAI55468.1; -; Genomic_DNA.
DR   RefSeq; WP_011374864.1; NC_007576.1.
DR   AlphaFoldDB; Q38WG4; -.
DR   STRING; 314315.LCA_1166; -.
DR   EnsemblBacteria; CAI55468; CAI55468; LCA_1166.
DR   KEGG; lsa:LCA_1166; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_1_9; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000002707; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..680
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279794"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        222..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        432..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   680 AA;  76556 MW;  4CAC0561A759970E CRC64;
     MKLATEKKTT RQKLSIAGML ITMGVVYGDI GTSPLYVMKS IVEGNGGIRN ISQDFVVGSI
     SLVFWTLMLM TTVKYVLIAL RADNNGEGGI FALYTLIRKQ AKWLVIPAII GGATLLADGM
     LTPAVTVTTA IEGLKGLPIN GNVLVSNQRE VIILTVTILS VLFFIQKFGT DLIGKSFGPI
     MLIWFTFIGA IGVMNLMGDL TMLKALNPYY AIHLLFSPEN KVGILILGSV FLATTGAEAL
     YSDMGHVGRH NIYGSWPYIA ACLVLNYFGQ GVWLLQHKEV AAYQNMTDFN PFFEAMPAQL
     KIPAILLATV AAIIASQALI SGSYTLVSEA IKLRLLPRIK VDYPAKLKGQ LYISIVNWIL
     WAVCLAVVFY FKNSAHMEAA YGLAITITML MTTILLFHYL GRREKRWFLA YVVLLFFGAI
     ETIFFIASAA KFMHGGYVTV LIAFVILFIM FVWYRSNSIK ESNTFKSSTV SLLAYKRQLH
     DLRNETSLPL YTTNLVYLSK PQAEPRGKNM VKKNILYSIL DKRPKRAQVY WFVAVNVTDE
     PYTAEYTVDT LGTDYIVSVQ LYLGFKMEQK VNIFIRQIIH EMIHNGELPA QPQHYTTIPN
     REVGDFSFVI IQEDLSPETQ IRAMDKVIVQ IRLWLEKFTD TPASWFGLEY SDVFVERIPL
     VLGRQKAINK YHLKRRQEES