ID   KUP_LIGS1               Reviewed;         674 AA.
AC   Q1WSN8;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=LSL_1284;
OS   Ligilactobacillus salivarius (strain UCC118) (Lactobacillus salivarius).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Ligilactobacillus.
OX   NCBI_TaxID=362948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCC118;
RX   PubMed=16617113; DOI=10.1073/pnas.0511060103;
RA   Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P.,
RA   Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C., Collins J.K.,
RA   Higgins D., Shanahan F., Fitzgerald G.F., van Sinderen D., O'Toole P.W.;
RT   "Multireplicon genome architecture of Lactobacillus salivarius.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01522};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000233; ABE00091.1; -; Genomic_DNA.
DR   RefSeq; WP_011476252.1; NC_007929.1.
DR   RefSeq; YP_536174.1; NC_007929.1.
DR   AlphaFoldDB; Q1WSN8; -.
DR   STRING; 362948.LSL_1284; -.
DR   PRIDE; Q1WSN8; -.
DR   EnsemblBacteria; ABE00091; ABE00091; LSL_1284.
DR   KEGG; lsl:LSL_1284; -.
DR   PATRIC; fig|362948.14.peg.1358; -.
DR   HOGENOM; CLU_008142_4_1_9; -.
DR   OMA; TILLYEW; -.
DR   Proteomes; UP000006559; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..674
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279795"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        342..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        397..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   674 AA;  76257 MW;  A43F4652C8C5A337 CRC64;
     MKVKRKIFWG ALITLGIVYG DIGTSPLYVM KALIMDAGGL NGLTEDYIIG CLSLVFWTLM
     LMTTIKYVLI ALRADNHGEG GIFALYALVR NKKKWLILPA LLGGAALLAD GTLTPAVTVT
     SAIEGLKGIS IGSQPWINTQ LEVNLVTFVI LLVLFLIQRF GTSFIGKAFG PLMLLWFSFL
     AIFGIVNLIH EPLVLRALSP HYGLMLLFSP ANKVGIFILG SVFLATTGAE ALYSDMGHVG
     KRSIYLTWPF VCGALVLNYF GQGAYLIKNL GNFKTTGDIF NPFYEMLPSS VYLFGVLIST
     IAAIIASQAL ITGSFTLVEE AVGLKLLPKM KVEHPSLSRG QIYIRTINWS LCICTLLVLV
     YFRTSERMEA AYGLAITITM LMTTILLSQY LKDKVNVVFN GIFLAVFLSV ELIFLISSLT
     KFTHGGYVTL LITLLILLIM VIWYFGNKLR DYLSDEEEWV SLRDYKDVLQ ELSNDDRIPL
     YISNLVMLTK VDKRTYKVKR ETLYSILDKS PKKAKVYWFV TVNTTSDPYT NYYTVDMMGT
     RNIVNLQLYL GFKMDHRVNL YLRQVVEDLI ENDIIDEQPQ KYTTMPGRKI GDFRFIIIQE
     LLSPNTRVRG WQHLLISARI FIQNHSTNPI QWFGLEFSEV KVEKVPLLLK KRRIPAMEQR
     MILNPKDVKR STKE