ID   KUP_METHJ               Reviewed;         611 AA.
AC   Q2FQC0;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Mhun_0881;
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1;
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01522};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000254; ABD40631.1; -; Genomic_DNA.
DR   RefSeq; WP_011447910.1; NC_007796.1.
DR   AlphaFoldDB; Q2FQC0; -.
DR   STRING; 323259.Mhun_0881; -.
DR   PRIDE; Q2FQC0; -.
DR   EnsemblBacteria; ABD40631; ABD40631; Mhun_0881.
DR   GeneID; 3923603; -.
DR   KEGG; mhu:Mhun_0881; -.
DR   eggNOG; arCOG05242; Archaea.
DR   HOGENOM; CLU_008142_4_2_2; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 8415at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..611
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279848"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        374..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        423..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   611 AA;  68438 MW;  14E7F322E8E961CC CRC64;
     MSRRTISKTM EHPSKTSIIK AAGLVFGDIG TSPIYTLAVL FLFLPPTPEN IMGAVSLIFW
     TLLIMVTVQY TFLAMRLSET GEGGTLVLKG ILIPLLKKPK GVAVFTLLAT LGISLMIGEC
     VITPAISILS AVEGVRQIPG FELIAQDWLI FLAILIALGL FLFQKRGTEG VSRTFGPVMV
     IWFLTLFISG AISVAFSPEI LLAINPIYAV EFFIHNGLLG FFSLSMIVLC ATGAEALFAD
     MGHLGREPIQ YAWGFVFIAV FFSYLGQAAY LLRNTDVINP LFEMIFSLSQ ILYIPFLLLM
     IIATIIASQA VISGIFSIIY QAITTHLLPM LPVDYTSDEL RTQIYINTVN WLLCIAVICV
     LLIFQYSERL ASAYGLAVTG TMSITGSFMI AIFLQRRKYL YMGIALIVTL VDITYFLSTV
     SKITHGGYLS LVIAAIPFTI VIIYTSGQRA LYRSMKPMGH DQFIKKYTRA YKTARHLRGT
     ALFFARSLDQ VPAYISRTMF NNEIIYEENV IISLDIKDEP YGFSWHFDKS IEPGLSHLSI
     SYGYMQIIDL MRIIRDAGIE EKTIFYGMEE IVTRNIIWKI FSAIKRLCPS FVQYYRLPSH
     KVHGVITRVE L