ID   KUP_METPP               Reviewed;         628 AA.
AC   A2SC47;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Mpe_A0174;
OS   Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Methylibium.
OX   NCBI_TaxID=420662;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1232 / LMG 22953 / PM1;
RX   PubMed=17158667; DOI=10.1128/jb.01259-06;
RA   Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W.,
RA   Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M.,
RA   Hristova K.R.;
RT   "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-
RT   proteobacterium Methylibium petroleiphilum PM1.";
RL   J. Bacteriol. 189:1931-1945(2007).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000555; ABM93136.1; -; Genomic_DNA.
DR   RefSeq; WP_011827775.1; NC_008825.1.
DR   AlphaFoldDB; A2SC47; -.
DR   STRING; 420662.Mpe_A0174; -.
DR   EnsemblBacteria; ABM93136; ABM93136; Mpe_A0174.
DR   KEGG; mpt:Mpe_A0174; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; FDTCMVT; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000000366; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..628
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000296768"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        295..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   628 AA;  68688 MW;  74565F5072C82E80 CRC64;
     MHSRSSDPPT GSKLAALTLG AVGVVYGDIG TSPLYALKEV FAHGRIDITP DNIYGILSLV
     VWTLTVIVSL KYVLLILRAD NNGEGGLIAM LALASTAVKE RPVLRRRLLI LGVFGTAIFF
     GDGVITPAIS VLSAVEGLEV AAPGLHRYVV PVTLVVLTLL FAAQRFGTGG IGKFFGPVTA
     VWFIVLALLG VVHIVENPAV LAALSPHYAL AFMWQHPGTA FVSLGAVVLC VTGAEALYAD
     MGHFGKRPIR LAWFSLVMPA LMINYFGQGA MLLQRPETVK NPFYEMAPEW ALYPLIVLAT
     LATVIASQAL ITAAFSVTKQ AIQLGYFPRL RVTHTSVKET GQIYVPFVNW GLYACIVLAV
     VTFGSSSKLA SAYGIAVTTD MLITTTMTFF VIRYSWKYPW ALCVAATGFF FLVDAMFFAA
     NAIKILDGGW FPLAIGAAMF TLMMTWKQGR RLMSERLREE AIDLKSFLES VFISPPTRVQ
     GTAVFLAAEQ GSTPNALLHN LKHNKVLHEQ NLFVTVRHHE VPWIPFSKRC EIESLGHCCW
     QVTLNFGFKN EPDVPEALAL LRGRGVQLDD METSYFLSRD IVIPTIGKGM AIWREKLFCS
     MHRNAAAAAD FLNLPTNRVV ELGSKVEI