ID   KUP_NITEC               Reviewed;         641 AA.
AC   Q0AIM8;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Neut_0522;
OS   Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=335283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 101675 / C91 / Nm57;
RX   PubMed=17991028; DOI=10.1111/j.1462-2920.2007.01409.x;
RA   Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S.,
RA   Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M., Wei X.;
RT   "Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas
RT   eutropha C91: implications for niche adaptation.";
RL   Environ. Microbiol. 9:2993-3007(2007).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000450; ABI58798.1; -; Genomic_DNA.
DR   RefSeq; WP_011633640.1; NC_008344.1.
DR   AlphaFoldDB; Q0AIM8; -.
DR   STRING; 335283.Neut_0522; -.
DR   EnsemblBacteria; ABI58798; ABI58798; Neut_0522.
DR   KEGG; net:Neut_0522; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000001966; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..641
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279804"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        267..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        384..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        437..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   641 AA;  70742 MW;  EE87F857BFF7F6EC CRC64;
     MALDSESSAS NRQGSRNEQD TNPRLTAALC LTALGVVYGD IATSPLYAFR EALHNIAPDS
     RTPESILGIL SLIFWALIIL VSIKYLLIIM RADNHGEGGI LALLALLRPW RGSPQHQRNV
     LIVLGLFGAA LLYGDGMITP AISVLSAMEG LEVAAPQLTS YIIPATTVIL VLLFMVQKRG
     TARIGRVFGP IMLVWFVVIA LLGLNGIIHH PQVLVAVNPY YGINFFTDNG WSAFRVLGGV
     FLALTGAEAL YADMGHVGRA PIRLMWFALV LPALLLNYFG QGALLLLDPH EAQPFFHLAP
     PSFLYSLVGL ATLATIIASQ AIISGVFSLT RQAIQLGQSP RLTLVQTSSE EIGQVYVPAA
     NWFMMIAAVW LVLHFRSSDN LAGAFGIAVS GTMVITTILA FFVMRERWHW NILTAVAVTV
     GFLIIDLAFF SSNLLKITDG GWFPLAIAVF IFTLMITWQQ GRQLLIQRIH KETESFQDFL
     QRIVTDPPVR VSGTAVFLTI HQHDTPPALL YQLIHNKALH EQVVLVTVIT EEVPRVPAAE
     RLEVMELSSG FHRIIVHYGF MQSPNVPVAL RACETLGLKI DLDTTTYYLS RASLIPTDER
     PGMALWRDRL FAFMSRNSAW PTAFYHLPPE HVIELGIQVE L