ID   KUP_NITHX               Reviewed;         666 AA.
AC   Q1QN78;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Nham_1497;
OS   Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Nitrobacter.
OX   NCBI_TaxID=323097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10229 / NCIMB 13809 / X14;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L.,
RA   O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T.,
RA   Gentry M.E., Bruce D., Richardson P.;
RT   "Complete sequence of chromosome of Nitrobacter hamburgensis X14.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000319; ABE62319.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1QN78; -.
DR   STRING; 323097.Nham_1497; -.
DR   EnsemblBacteria; ABE62319; ABE62319; Nham_1497.
DR   KEGG; nha:Nham_1497; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; AADQFEI; -.
DR   Proteomes; UP000001953; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..666
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279802"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        324..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        381..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        441..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        463..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   666 AA;  71955 MW;  1E0787A5FFEE0BF8 CRC64;
     MQAVNIIRWI DGPVLVGDSP GSKPPSERLQ DTMAVSDPPV EAAGEASATR SGFWALTLGS
     IGVVFGDIGT SPLYAFREAV SHAAQQGTVT PVIVLGVLSL ILWSLFIVVT AKYVLLLLRA
     DNNGEGGTLS LMALGQRALG RQSLLLLALG VVGASMFIGD SMITPAISVL SAVEGLKLAA
     PEFGNYVVPL TLLILVMLFA VQSRGTASVA SAFAPVMALW FVAIAVLGAL HIHEDPSVLL
     AVNPWYAIHF LLNHGLIGLV IMGLVFLSVT GGEALYADLG HFGRKPIQAA WFCLVLPALL
     LNYFGQGALI LAHPDAIENP FYRLAPAPMI LPLVILATAA TVIASQAVIT GAYSLIRQAV
     QLGLLPRFEV RYTSETHAGQ IYLPRVNILL LIGVLLLVLL FRTSSGLASA YGIAVSTTMV
     ADGIMGFVVV WKLWNWRAAT AAALVVPLVV VDIMFFSANL LKLLDGAWVP LLFGLIMVVL
     IWTWRRGAAI LIKKTRRTEV PLLDLIKSLE KRPPHIVKGT AVFLTSDPNF VPTALLHNLK
     HNKVLHEHNV ILTIETAQTP RVDPSERVRM ENISEKFSTV SLRFGFMESP NVPKALVIAR
     KLGWQFDIMA TSFFVSRRSL KASAQSGMPV WQDRLFIAMS RSANDAINYF QIPTGRVVEV
     GTQVII