ID   KUP_NITMU               Reviewed;         632 AA.
AC   Q2YCL2;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Nmul_A0201;
OS   Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=323848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25196 / NCIMB 11849 / C 71;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT   25196.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000103; ABB73509.1; -; Genomic_DNA.
DR   RefSeq; WP_011379563.1; NZ_FNVK01000010.1.
DR   AlphaFoldDB; Q2YCL2; -.
DR   STRING; 323848.Nmul_A0201; -.
DR   EnsemblBacteria; ABB73509; ABB73509; Nmul_A0201.
DR   KEGG; nmu:Nmul_A0201; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; FDTCMVT; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000002718; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..632
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279805"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        296..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        376..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        404..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        429..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   632 AA;  68520 MW;  E77B329A9D443529 CRC64;
     MTNQQMPSGH SLERQPLSLL CLAALGVVYG DIGTSPLYVM KTVFDPIHGL AVTESNVIGI
     ISLIFWTIMI VVSLKYVTLI LRADNHGEGG IMALLSLASS SVTDRPRLHN ILFLIGAFGA
     ALFFGDGVIT PAISVLSAVE GLEVATPLLQ PYVLPITVVV LIALFMLQQR GTGGIGALFG
     PVMVIWFVSL GLVGLINIAG APQIVAAFNP MYAFAFCISN GWLAFIALGA VVLAVTGGEA
     LYADMGHFGA KPIRLAWYGG VLPALTLNYL GQGALLLANP AAISNPFFLL FPSWALYGAV
     GLATAATVIA SQSVISGVFS VTRQAIQLGF LPRMQIRHTS ERKIGQIYIP FVNWTLLSVV
     LMAVLGFGSS SNLASAYGVA VTTTMVIETT LTFFVLRYVW NYPFLLGILV TAFFLAIDSA
     FFSATILKVA QGGWFPLVIG SVIFFIMITW SRGRQMLVDH LRSVAIPLQS FLESLIAHPP
     TRVAGTSVFL TANPDGVPHA LLHNLAHNQV LHERVVFLTV TYQETPWVPV EQRISIKPLM
     ENCYQITVRY GFKDEANLPY ALELCEPHGL VFEPLRTSYF LSREIVVPSP GTGMSLWRER
     LFAAMVRNAS NAAEYFKLPA NRVLELGARV EI