ID   KUP_PARXL               Reviewed;         628 AA.
AC   Q13X42;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Bxeno_A2809;
GN   ORFNames=Bxe_A1608;
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400;
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA   Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA   Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA   Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT   shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000270; ABE31347.1; -; Genomic_DNA.
DR   RefSeq; WP_011488933.1; NZ_CP008760.1.
DR   AlphaFoldDB; Q13X42; -.
DR   STRING; 266265.Bxe_A1608; -.
DR   EnsemblBacteria; ABE31347; ABE31347; Bxe_A1608.
DR   KEGG; bxb:DR64_3767; -.
DR   KEGG; bxe:Bxe_A1608; -.
DR   PATRIC; fig|266265.5.peg.2950; -.
DR   eggNOG; COG3158; Bacteria.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..628
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279775"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        294..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        342..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        426..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   628 AA;  68677 MW;  773A9897D10BF405 CRC64;
     MTDNNHEHKQ PLPSLAIAAI GVVFGDIGTS PLYSLKEAFS PSHGIPLTDQ SILGVISLLF
     WAIVIVVGVK YVLFVMRADN NGEGGVLALM ALALRSLDEK SKMAGLLMML GIFGACMFYG
     DAVITPAISV ISAVEGLEIA APHLSHLVLP LTIVILILLF WIQRHGTAMV GRLFGPIMVL
     WFVVLAALGL WHILQSPSVI RALNPCYAYT FMAAHVLQAY VVLGSVVLVL TGAEALYADM
     GHFGAKPIRM AWYVLVMPSL VLNYFGQGAL LMHDPKAIEN PFFLLAPDWA LLPLVVLSTI
     ATVIASQAVI SGAYSLTSQA IQLGYVPRMK ILHTSELAIG QIYVPVVNWM LLFIILCIVI
     AFKSSDNLAA AYGIAVTATM VITTILACVV MVKVWNWNKL LVALIIGVFM TVDLGFFGAN
     LLKVEEGGWL PLGIGALLFF LLMTWYKGRM IVKERTAADG IPLMPFLQGL LAHPPHRVSG
     TAIYLTGSDS LVPVSLLHNL KHNKVLHERT IFLTFVTRDI PYVNDADRVT VKDIDGGLYL
     VKAAYGFNET PDVKAVLLEV GRTHDMTFEL MDTSFFLARE TVVPTQLPGM SVWRERVFAW
     MHQNAAKPTD FFSIPANRVV ELGTKIEI