ID   KUP_POLAQ               Reviewed;         647 AA.
AC   A4SYW3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Pnuc_1463;
OS   Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 /
OS   QLW-P1DMWA-1) (Polynucleobacter necessarius subsp. asymbioticus).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Polynucleobacter.
OX   NCBI_TaxID=312153;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18221 / CIP 109841 / QLW-P1DMWA-1;
RX   PubMed=22675600; DOI=10.4056/sigs.2395367;
RA   Meincke L., Copeland A., Lapidus A., Lucas S., Berry K.W., Del Rio T.G.,
RA   Hammon N., Dalin E., Tice H., Pitluck S., Richardson P., Bruce D.,
RA   Goodwin L., Han C., Tapia R., Detter J.C., Schmutz J., Brettin T.,
RA   Larimer F., Land M., Hauser L., Kyrpides N.C., Ivanova N., Goker M.,
RA   Woyke T., Wu Q.L., Pockl M., Hahn M.W., Klenk H.P.;
RT   "Complete genome sequence of Polynucleobacter necessarius subsp.
RT   asymbioticus type strain (QLW-P1DMWA-1(T)).";
RL   Stand. Genomic Sci. 6:74-83(2012).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01522};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000655; ABP34677.1; -; Genomic_DNA.
DR   RefSeq; WP_011903300.1; NC_009379.1.
DR   AlphaFoldDB; A4SYW3; -.
DR   STRING; 312153.Pnuc_1463; -.
DR   EnsemblBacteria; ABP34677; ABP34677; Pnuc_1463.
DR   GeneID; 31481853; -.
DR   KEGG; pnu:Pnuc_1463; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AIRVSWL; -.
DR   Proteomes; UP000000231; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..647
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000333309"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        418..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        443..463
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   647 AA;  71899 MW;  78F672F7D0EFD01F CRC64;
     MSVSNPEFSE SSILRPVEIS RQTHPHKKGA SIALMFAAIG IVFGDIGTSP LYALKECFSP
     DHGIPFSADA VYGVISMVFW AFAIVVSLKY VLFVMRANNH GEGGILALMA LALRTAPNGS
     KRSLLIIMAG VFGACMFYGD AIITPAISVL SAVEGLEVIS SDLTRFVLPI TVLILVILFF
     IQKTGTEVVG KLFGPIMMVW FITIGLMGLH QVIQNPAIFA AVNPMFAIRF LIEHSLQGFI
     VLGAVFLVLT GAEALYADMG HFGIRPIRMG WFFIVMPCLL LNYFGQGAMF LANPETISNP
     FFLMVPEVFV FPLVILATAA TVIASQAVIS GAFSMTSQAI LLGFVPRMKV RHTSDREIGQ
     IYMPFVNWTL LFLVIVVVLA FKKSENLAAA YGIAVTTTMI VTTLLAAIVM RVVWRWNTIL
     VTLVIGAFLT VDLAFLTANL LKIMEGGWFP LLLGAICFLF LMTWYQGRKL LRQNAVNNGI
     ELKGFIDALM QHPPHRVEGT ALFLTAHVDY VPVSFLHNLK HNHVLHERVF FLKVSIWDVP
     YVKDEERITL RDMGNGIYVV RAVYGFNETP DMGQIIELIE KSADLKFDMM NTSFFLSRDT
     IVSTEIPGMA MWRERLFCWM YQNAGRQSDF FKIPANRLVE LGAKVEI