ID   KUP_POLNA               Reviewed;         622 AA.
AC   A1VTR7;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Pnap_3749;
OS   Polaromonas naphthalenivorans (strain CJ2).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=365044;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CJ2;
RX   PubMed=19453698; DOI=10.1111/j.1462-2920.2009.01947.x;
RA   Yagi J.M., Sims D., Brettin T., Bruce D., Madsen E.L.;
RT   "The genome of Polaromonas naphthalenivorans strain CJ2, isolated from coal
RT   tar-contaminated sediment, reveals physiological and metabolic versatility
RT   and evolution through extensive horizontal gene transfer.";
RL   Environ. Microbiol. 11:2253-2270(2009).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000529; ABM39045.1; -; Genomic_DNA.
DR   RefSeq; WP_011803111.1; NC_008781.1.
DR   AlphaFoldDB; A1VTR7; -.
DR   STRING; 365044.Pnap_3749; -.
DR   EnsemblBacteria; ABM39045; ABM39045; Pnap_3749.
DR   KEGG; pna:Pnap_3749; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000000644; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..622
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000292619"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        337..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   622 AA;  67864 MW;  6AB8D824523D7B9F CRC64;
     MTSQKSSLAV LTVGAIGVVY GDIGTSVLYA IKEVFGSGHV PFTPDNVYGI LSIFFWTLTV
     IVSLKYVSLV LRADNNGEGG LIAMLALAST AVQDRPELRK VLLLVGIFGT SLFYGDGVIT
     PAISVLSAVE GLEVISPTFT KAVIPTTLVI LFGLFAMQKH GTAGIGKFFG PITIVWFAVL
     ALLGVSQIVT HPEILFALSP HYALMFMWEN PGITFIILGA VVLCVTGAEA LYADLGHFGK
     KPIRLAWFSV VMPSLVLNYF GQGALLLSNP AAVKNPFYLM APDWALIPLV VLATLATVIA
     SQALITGAFS VTKQAIQMGY LPRLRILHTS VRDTGQIYMP FVNWGLFVTI VLAVVMFRSS
     SNLAAAYGIA VCTDMLITTI LTFYVIRYGW KYPLALCIAA TSVFFLVDFA FFASNLMKLF
     AGGWFPLVIG GAVFTLMITW KQGRQILNEK LRTDAIDLSS FLDAVFVSPP LRVEGTAVFM
     TAEPGIVPNA MLHNLKHNKV LHDQNLFVTV VNHEVPWIGM DKRLQVESLG HDCWQVNIHY
     GFKNDLDLPR ALQQIKNRGC QLEPMTTSYF LSRDTVIPTI GSGMAAWREK LFAQMHHNAS
     GAADFLNLPN NSVVELGSKI EI