ID   KUP_PSEA8               Reviewed;         634 AA.
AC   B7UY17;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=PLES_43991;
OS   Pseudomonas aeruginosa (strain LESB58).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=557722;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LESB58;
RX   PubMed=19047519; DOI=10.1101/gr.086082.108;
RA   Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I.,
RA   Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A.,
RA   Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D.,
RA   Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C.;
RT   "Newly introduced genomic prophage islands are critical determinants of in
RT   vivo competitiveness in the Liverpool epidemic strain of Pseudomonas
RT   aeruginosa.";
RL   Genome Res. 19:12-23(2009).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; FM209186; CAW29154.1; -; Genomic_DNA.
DR   RefSeq; WP_003104754.1; NC_011770.1.
DR   AlphaFoldDB; B7UY17; -.
DR   PRIDE; B7UY17; -.
DR   KEGG; pag:PLES_43991; -.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   OMA; AADQFEI; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..634
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_1000190274"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        379..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        431..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   634 AA;  68735 MW;  5D4CBA5F70CCBE99 CRC64;
     MSDAATRAEE TSEGHSSSAI GLMVGAVGVC YGDIGTSPLY TLKEVFIGGY GVQANHDGVL
     GVLSLIFWSL VWVVSIKYVI FVLRADNQGE GGVMALSALA RRAAAPFGRL QTFVVVAGLI
     GAALFYGDSM ITPAISVLSA VEGLEIAFDG LEHWTVPLAL IVLIGLFLIQ KHGTARIGIL
     FGPVMVLWFG ALAALGVYGV IQQPEVLQAM NPVWAVRFFS SHPGIGVAIL GATVLALTGA
     EALYADMGHF GRKPIARAWF LLVLPALVLN YFGQGATILS NAEAARNPFY LLAPGWALLP
     MVALSTLATV IASQAVISGA FSLTRQAIQL GYVPRMTIQH TSSHEQGQIY IGGVNWALMV
     GVVLLVLGFE SSASLAAAYG VAVTGTMLIT TLLMGVVIWR LWKWPLWLGV PFFCVMLAVD
     SLFFAANLPK VIQGGAFPVI AGIVIFILMS TWKRGRQLLV ERLDEGSLPL SVFISSMRVQ
     PPHRVQGTAV FLTARTDAVP HALLHNLLHN QVLHEQVVLL TVVNEDSPRV SPDRRFEVEA
     YGDGFFRVIL HFGFMEEPDI PAALRLCHLN ELDFSPMRTT YFLSRETVIP SKRIGMARWR
     EGLFAFLLKN ANGNLRYFNL PLNRVIELGT QVEI