KUP_PSEAB
ID KUP_PSEAB Reviewed; 634 AA.
AC Q02I77;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=PA14_52400;
OS Pseudomonas aeruginosa (strain UCBPP-PA14).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCBPP-PA14;
RX PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G.,
RA Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT combinatorial.";
RL Genome Biol. 7:R90.1-R90.14(2006).
CC -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR EMBL; CP000438; ABJ10076.1; -; Genomic_DNA.
DR RefSeq; WP_003140804.1; NZ_CP034244.1.
DR AlphaFoldDB; Q02I77; -.
DR EnsemblBacteria; ABJ10076; ABJ10076; PA14_52400.
DR KEGG; pau:PA14_52400; -.
DR HOGENOM; CLU_008142_4_2_6; -.
DR OMA; AADQFEI; -.
DR BioCyc; PAER208963:G1G74-4409-MON; -.
DR Proteomes; UP000000653; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01522; Kup; 1.
DR InterPro; IPR003855; K+_transporter.
DR InterPro; IPR023051; K+_uptake_low_affin.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..634
FT /note="Probable potassium transport system protein kup"
FT /id="PRO_0000279809"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ SEQUENCE 634 AA; 68715 MW; 7A9A1E3F5DADDD92 CRC64;
MSDAATRAEE TSEGHSSSAI GLMVGAVGVC YGDIGTSPLY TLKEVFIGGY GVQANHDGVL
GVLSLIFWSL VWVVSIKYVI FVLRADNQGE GGVMALSALA RRAAAPFGRL QTFVVVAGLI
GAALFYGDSM ITPAISVLSA VEGLEIAFDG LEHWTVPLAL IVLIGLFLIQ KHGTARIGIL
FGPVMVLWFG ALAALGVYGV IQQPEVLQAM NPVWAVRFFG SHPGIGVAIL GATVLALTGA
EALYADMGHF GRKPIARAWF LLVLPALVLN YFGQGATILS NAEAARNPFY LLAPGWALLP
MVALSTLATV IASQAVISGA FSLTRQAIQL GYVPRMTIQH TSSHEQGQIY IGGVNWALMV
GVVLLVLGFE SSASLAAAYG VAVTGTMLIT TLLMGVVIWR LWKWPLWLGV PFFCVMLAVD
SLFFAANLPK VIQGGAFPVI AGIVIFILMS TWKRGRQLLV ERLDEGSLPL SVFISSMRVQ
PPHRVQGTAV FLTARTDAVP HALLHNLLHN QVLHEQVVLL TVVNEDSPRV PPDRRFEVEA
YGDGFFRVIL HFGFMEEPDI PAALRLCHLN ELDFSPMRTT YFLSRETVIP SKRIGMARWR
EGLFAFLLKN ANGNLRYFNL PLNRVIELGT QVEI