ID   KUP_RHOJR               Reviewed;         657 AA.
AC   Q0SIZ9;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=RHA1_ro00652;
OS   Rhodococcus jostii (strain RHA1).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Rhodococcus.
OX   NCBI_TaxID=101510;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RHA1;
RX   PubMed=17030794; DOI=10.1073/pnas.0607048103;
RA   McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C.,
RA   Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H.,
RA   Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H.,
RA   Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R.,
RA   Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W.,
RA   Eltis L.D.;
RT   "The complete genome of Rhodococcus sp. RHA1 provides insights into a
RT   catabolic powerhouse.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01522};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000431; ABG92487.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q0SIZ9; -.
DR   STRING; 101510.RHA1_ro00652; -.
DR   EnsemblBacteria; ABG92487; ABG92487; RHA1_ro00652.
DR   KEGG; rha:RHA1_ro00652; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_11; -.
DR   OMA; AADQFEI; -.
DR   Proteomes; UP000008710; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..657
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279824"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        394..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        447..467
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   657 AA;  70418 MW;  9C8C43A6318423A0 CRC64;
     MGSGPADEEH TVDTEPGVSP PRRTVGGRET VRAAVVVGAL GVVFGDIGTS PIYTIQTVFN
     PEDPHPVPIS TNNVYGVVSL IFWSVMLIVT ATYVLLVMRA DNDGEGGVMA LITLLRRMGA
     VRGSRVTAVL AGLGIFGAAL FFGDSMITPA ISVLSAVEGL KVVEPGLEEW IVPITAVIIV
     ALFSVQRRGT AAVGRLFGPV MIVWFVSIGA CGVSGIARHP EILKALSPTY ALSFFFGHFG
     IAFFALAAVV LAVTGAEALY ADMGHFGRRA ITRGWLVLVL PACVLSYLGQ GALLLGDQSA
     VSSPFFLLAP GWARWPMVLL ATAATVIASQ AVITGAYSVA SQAAQLGYLP RLRVAHTSES
     TIGQIYVPWI NWVLMVSVLT LVFAFRSSAA LAYAFGMAVT GTITITTLLF FYIVRTRWGT
     PLWLVVCGAG CLLAVDLLFL AANLTKLVHG AWLPLLIALT AFTVMTTWQR GRAIVTRARE
     RAEGSLGDFV GQLHDYRPPL VRVPGTAVFL NRGKQTAPLA MRANVEHNRV LQQHVVIMSI
     NTLPVPRVPD TERTEIDKLG YAEDGIVHVT AFFGYMDAPN IPDVLRLLDP AETEGPIAVD
     SASYFLSKIE LTMGTAPTMA TWRKRLFIAT SYITADAAEY FGLPGERTVI MGSRIDV