ID   KUP_SPHAL               Reviewed;         653 AA.
AC   Q1GSZ7;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   27-JUN-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Sala_1512;
OS   Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)
OS   (Sphingomonas alaskensis).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingopyxis.
OX   NCBI_TaxID=317655;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13593 / LMG 18877 / RB2256;
RX   PubMed=19805210; DOI=10.1073/pnas.0903507106;
RA   Lauro F.M., McDougald D., Thomas T., Williams T.J., Egan S., Rice S.,
RA   DeMaere M.Z., Ting L., Ertan H., Johnson J., Ferriera S., Lapidus A.,
RA   Anderson I., Kyrpides N., Munk A.C., Detter C., Han C.S., Brown M.V.,
RA   Robb F.T., Kjelleberg S., Cavicchioli R.;
RT   "The genomic basis of trophic strategy in marine bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:15527-15533(2009).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000356; ABF53225.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1GSZ7; -.
DR   STRING; 317655.Sala_1512; -.
DR   EnsemblBacteria; ABF53225; ABF53225; Sala_1512.
DR   KEGG; sal:Sala_1512; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; FDTCMVT; -.
DR   Proteomes; UP000006578; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..653
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000279833"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        268..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        401..421
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        429..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        451..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   653 AA;  70742 MW;  99DCD8A6BEA88BE1 CRC64;
     MTAESQRAAE GVATAIEAAA ETGHHGHGPH GDGKLKLAVG AVGVVFGDIG TSPLYAFRET
     FAGHHPIEPD RLHIYGVLSL VFWSMMLVVT FKYVMTIMRA DNKGEGGSLA LLALISRSSE
     GKRWTWPIVL LGVFATALFY GDSMITPAMS VLSATEGLSY VDKGFEPYIV PIALGILIGL
     FAIQARGTAK VGALFGPIML LYFLMLAGLG ILHIGNNPWI IVETLNPVNA LRFFYLDGFT
     AFIALGAVVL AVTGAEALYA DMGHFGRGPI GLSWLSFVLP ALMLNYMGQG AMVLAAEAGP
     RTELIADPFF QMMPQFLELP VVILALLATI IASQAVISGA FSLTQQAIQL GFMPRLRVEH
     TSASAAGQIY IPIVNWGLMV MVILLVLGFG SSSNLAAAYG IAVTGAMFID TCLMSVVLFT
     LWKWPAWKAL PVLAVFFIVD IAYFGANLIK VPDGGWVPLV IGLTIFTLLT TWSRGRKLMQ
     EEMAEGAMPI PIFVKSAANS ATRVPGTAVF MTSSSDGVPH ALLHNLKHNK VLHERIILLT
     IKIADVPFVP ESKLCQLEDL GQGFHRLVLN YGFMQPIDVP EALMRVTSCG GEFKMLETSF
     FLSRQTLIAA KKPGMPIWRE KLFAWMLRNS ESAMEYFRLP SNRVVELGSQ VAI