ID   KUP_THEVB               Reviewed;         625 AA.
AC   Q8DHB0;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=tll2049;
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; BA000039; BAC09601.1; -; Genomic_DNA.
DR   RefSeq; NP_682839.1; NC_004113.1.
DR   RefSeq; WP_011057884.1; NC_004113.1.
DR   AlphaFoldDB; Q8DHB0; -.
DR   STRING; 197221.22295776; -.
DR   PRIDE; Q8DHB0; -.
DR   EnsemblBacteria; BAC09601; BAC09601; BAC09601.
DR   KEGG; tel:tll2049; -.
DR   PATRIC; fig|197221.4.peg.2145; -.
DR   eggNOG; COG3158; Bacteria.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..625
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000209065"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        398..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        423..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   625 AA;  69573 MW;  8BA02CE11192ED32 CRC64;
     MTKANAGHPP SRLLMLGALG VVYGDLGTSP LYAFEETFNP LHVLAVTPAN IYGILSLILW
     GLVLIPTLKY ATFALRADND GEGGIFPLMA LVLSRIRLSS HWRRRVIIFG LVGAAMFYGD
     STITPAISVL SAIEGLEVLS PQLGSWTVPL TVVILVGLFW FQHRGTTQVG QVFGPIMFLW
     FMTLGLLGTI HIFEQPTILN ALNPWWGVQL FYSQPAQVFF LLGVVILALT GAEAMYADMG
     HFGIQPIRLA WYRLVFPALA LNYLGQGAFI LKHPTATHHL FFQLAPEWSV LPLVILSTLA
     TVIASQAVIS GAFSMTAAAI KLGYLPRLRI DVTDDYHRGQ IYIPVINWLL LVTVLLLVMT
     FRKSSELAGA YGLAVNLTMV VTTLCLILVA RHLWRWSIVQ ISLVWVSILV IEIAFLIGNA
     LKIPYGGWYP LAFGGVVYML LGTWRQGQVL LRQQLLQANA RFSLKELLSQ GVARVPGIAV
     FFSPLPDMIP LSFIQNLQHN HVLHQQTIFI HLATANLPHV PLSEQLTYRV TDVGIYEIIL
     TSGFRDRPDL RLALETCQQA LNLPLNGQPM SFFLGRRTII PTHARGMTYW QKVVFAWLYR
     NAEDATSYFR LPSEQVVELG IQVEI