KUP_XANCP
ID KUP_XANCP Reviewed; 635 AA.
AC Q8P6E6;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=XCC3024;
OS Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB
OS 528 / LMG 568 / P 25).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=190485;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25;
RX PubMed=12024217; DOI=10.1038/417459a;
RA da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R.,
RA Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr.,
RA Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G.,
RA Cannavan F., Cardozo J., Chambergo F., Ciapina L.P., Cicarelli R.M.B.,
RA Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B.,
RA Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F.,
RA Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T.,
RA Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A.,
RA Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J.,
RA Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M.,
RA Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A.,
RA Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A.,
RA Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M.,
RA Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P.;
RT "Comparison of the genomes of two Xanthomonas pathogens with differing host
RT specificities.";
RL Nature 417:459-463(2002).
CC -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR EMBL; AE008922; AAM42295.1; -; Genomic_DNA.
DR RefSeq; NP_638371.1; NC_003902.1.
DR RefSeq; WP_011038140.1; NC_003902.1.
DR AlphaFoldDB; Q8P6E6; -.
DR STRING; 340.xcc-b100_1172; -.
DR EnsemblBacteria; AAM42295; AAM42295; XCC3024.
DR GeneID; 58012432; -.
DR KEGG; xcc:XCC3024; -.
DR PATRIC; fig|190485.4.peg.3226; -.
DR eggNOG; COG3158; Bacteria.
DR HOGENOM; CLU_008142_4_2_6; -.
DR OMA; AADQFEI; -.
DR Proteomes; UP000001010; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR HAMAP; MF_01522; Kup; 1.
DR InterPro; IPR003855; K+_transporter.
DR InterPro; IPR023051; K+_uptake_low_affin.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..635
FT /note="Probable potassium transport system protein kup"
FT /id="PRO_0000209069"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 377..397
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ SEQUENCE 635 AA; 69712 MW; 6A64C9BC267A5139 CRC64;
MSHTPTPAAG SGHAPANGHM ALVIGAIGVV FGDIGTSPLY TLKEAFSPHY GLTSDHDTVL
GVLSLAFWAL MITVTLKYVT IIMRADNEGE GGIMALMALT QRTLKQGSRS AYVVGILGIF
GASLFFGDGV ITPAISVMGA VEGLEIAAPS LHPFIVPITV VVLLVVFMVQ RFGTEKVGKV
FGPITCLWFL SLGAIGIWNI VDAPEVLKAF NPWWAIRFFM EHGWHGVFIL GAVVLAVTGG
EALYADMGHF GARPIRHGWY FFVLPMLLLN YLGQGALVLN HPAALKNPFF EAVPSWALYP
MIILATLAAV IASQAVITGA YSVARQAMQL GYIPRMLIKH TSRDTIGQIY VPGINWLLMV
MVIALVLIFR SSTNLAVAYG ISVSMTMLID TLLLALVARS LWPRWRNWVL PLCVVFFIIE
LAFVIANGAK LLQGAWFPLA LGIVVFTLMR TWRRGRALLR EEIRKDGIRI DSFLPGLMLA
PPARVPGMAV FLTADPMVVP HALMHNLKHN KVLHERNIFL NVDTLPIPYA PADKRLQIES
IGDEFYRVYV RFGFMETPDV PLALMRSCDQ GGIHFDPMDT TFFASRETIV ASANRGMPIW
RDKLFALMHR NAAPATGFFR IPGNRLVELG AQVEI
