ID   KUP_XANP2               Reviewed;         628 AA.
AC   A7IBQ1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Xaut_0185;
OS   Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Xanthobacteraceae; Xanthobacter.
OX   NCBI_TaxID=78245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1158 / Py2;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA   Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Tapia R., Brainard J., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.;
RT   "Complete sequence of chromosome of Xanthobacter autotrophicus Py2.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000781; ABS65444.1; -; Genomic_DNA.
DR   AlphaFoldDB; A7IBQ1; -.
DR   STRING; 78245.Xaut_0185; -.
DR   EnsemblBacteria; ABS65444; ABS65444; Xaut_0185.
DR   KEGG; xau:Xaut_0185; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; GHETIIP; -.
DR   PhylomeDB; A7IBQ1; -.
DR   Proteomes; UP000002417; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..628
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_1000190287"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        295..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        398..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   628 AA;  67859 MW;  0F3ED6E70220D7F9 CRC64;
     MALSFSRDRT RPLPFAAEIG ALGVVFGDIG TSPLYALKQG VLAVGGTNFL GGDVLGLLSL
     ITWSIILSVT VKYVMLVLRA DNDGEGGILA LVTLLDLHRS ALGMRWYLLA AGLLGAAMLI
     GDGVLTPAMS VLSAIEGLQV ISPELEHWVV TLTVLVLLAV FLSQRLGTER IASFFGPIML
     MWFGSLGALG VYGILQAPQV LAGLDPRYGI MLMVNHPGLA GVILGACFLA VTGGEALYAD
     LGHFGRPVIA RAWLFVAMPA LLLNYFGQGA ILLVDPNAVR NPFYDLCPDV FDIPLLFLAT
     AATVIASQSI ITGVFSLAKQ AIELGYLPPM RIRYTSEHNE QHIYVGRLNW LLMIACIAVV
     LGFEASDRLA SAYGIAVAFA MVTTSILFIA QVHRSWGWPA PAVWAMATGL LTIDFAFASA
     NMTKIHDGGW LPLSIAAAII FVMVSWRRGL EGVVAQQVRF TEPLDSFVAR KDRVNDVEAP
     RTAIFLSRAG AMTPVALSRM ADLLKVRFEK AVIVSVWIAA RPRVSVEDRV KVTTLNEGFV
     RVDLRFGYMQ QIDVPSVLGP ALSARGIDPD AAIYVIGHER IIPPDEVTKI KDVVAHVFAF
     LARNAERSVD RFGLPRARTV EIGYPVKL