ID   KUP_ZYMMO               Reviewed;         652 AA.
AC   Q5NN77;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Probable potassium transport system protein kup {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=ZMO1209;
OS   Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Zymomonadaceae; Zymomonas.
OX   NCBI_TaxID=264203;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31821 / ZM4 / CP4;
RX   PubMed=15592456; DOI=10.1038/nbt1045;
RA   Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H.,
RA   Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J.,
RA   Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y., Kang H.L., Lee S.Y., Lee K.J.,
RA   Kang H.S.;
RT   "The genome sequence of the ethanologenic bacterium Zymomonas mobilis
RT   ZM4.";
RL   Nat. Biotechnol. 23:63-68(2005).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; AE008692; AAV89833.1; -; Genomic_DNA.
DR   RefSeq; WP_011241029.1; NZ_CP035711.1.
DR   AlphaFoldDB; Q5NN77; -.
DR   STRING; 264203.ZMO1209; -.
DR   PRIDE; Q5NN77; -.
DR   EnsemblBacteria; AAV89833; AAV89833; ZMO1209.
DR   GeneID; 58026980; -.
DR   KEGG; zmo:ZMO1209; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; FDTCMVT; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000001173; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..652
FT                   /note="Probable potassium transport system protein kup"
FT                   /id="PRO_0000209075"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        314..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        391..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        444..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   652 AA;  71915 MW;  7E203191D1000211 CRC64;
     MSNDTSPGTS SVDSKSSDPS YGVPGHSHSD KDLLKLSLGA IGIVFGDIGT SPLYALKECF
     KGHHQLPVDD FHIYGLVSLI FWTMGLVVTV KYVMFIMKAD NKGEGGSMSL LSLIIRGANP
     KLSRWLIVLG VFATALFYGD SMITPAMSVL SAVEGLTVIE PSFDSWVPPV SVVILIGLFC
     IQARGTESVG RLFGPIMLVY FATLAILGAF NIITRSPAIL LALNPYYAIH FFASDPLQGF
     WALGSVVLSV TGAEALYADM GHFGRQPISL GWYWVVFPAL TLNYLGQCAL LSADHEAIAN
     PFYFLAPDFL RVPLIILATF AAVIASQAVI TGAFSVTQQA IQLGYIPRLR VNHTSASTVG
     QIYIPSVNWV LMFMVMVLIA MFKNSTNLAN AYGIAVTGTM FITSCMMGVL VHRVWHWKAW
     QSIPLVSFFL LIDGAFFLSN VTKIPEGGWF PLLVGFVVFT MLMTWSRGRH LMAERMRQVA
     MPIQLFIRSA AASAVRIPGT AIFLTPEDDG VPHALLHNLK HNKILHERVI LLTVKIEDVP
     YVDPHYRASM SSLEDGFYRL IVRYGFMEEP DVPLALNKIE QSGPMLRMDD TSFFISRQTL
     IPSTHTSMAI WREKLFAWML RNSESATEFF KLPSNRVVEL GSQIELVGSN GK