ID   KV03_RABIT              Reviewed;         109 AA.
AC   P01684;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Ig kappa chain V region 3374;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=1094456; DOI=10.1073/pnas.72.6.2180;
RA   Margolies M.N., Cannon L.E. III, Strosberg A.D., Haber E.;
RT   "Diversity of light chain variable region sequences among rabbit antibodies
RT   elicited by the same antigens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 72:2180-2184(1975).
CC   -!- MISCELLANEOUS: This chain was obtained from antibody to type III
CC       pneumococci and was isolated from the serum of a single rabbit.
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DR   PIR; A01947; KVRB37.
DR   AlphaFoldDB; P01684; -.
DR   SMR; P01684; -.
DR   PRIDE; P01684; -.
DR   Proteomes; UP000001811; Unplaced.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Immunity; Immunoglobulin;
KW   Reference proteome.
FT   CHAIN           1..>109
FT                   /note="Ig kappa chain V region 3374"
FT                   /id="PRO_0000059722"
FT   REGION          1..24
FT                   /note="Framework-1"
FT   REGION          25..35
FT                   /note="Complementarity-determining-1"
FT   REGION          36..50
FT                   /note="Framework-2"
FT   REGION          51..57
FT                   /note="Complementarity-determining-2"
FT   REGION          58..89
FT                   /note="Framework-3"
FT   REGION          90..98
FT                   /note="Complementarity-determining-3"
FT   REGION          99..108
FT                   /note="Framework-4"
FT   NON_TER         109
SQ   SEQUENCE   109 AA;  11512 MW;  E79294813E1318AF CRC64;
     ADIVMTQTPA SVSAAVGGTV TINCQASQNI DSWLAWYQQK PGQPPKVLIY RTSTLASGVP
     SRFKGSRSGT EFTLTISDLE CADAATYYCQ SYYSISSAFG GGTEVVVKG