ID   KV07_RABIT              Reviewed;         108 AA.
AC   P01688;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Ig kappa chain V region K-25;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=241319; DOI=10.1042/bj1470235;
RA   Jaton J.-C.;
RT   "Comparison of the amino acid sequences of the variable domains of two
RT   homogeneous rabbit antibodies to type III pneumococcal polysaccharide.";
RL   Biochem. J. 147:235-247(1975).
CC   -!- MISCELLANEOUS: Residues 109-139 of the constant region are identical
CC       with the corresponding residues of rabbit 4135 kappa chain.
CC   -!- MISCELLANEOUS: This chain was obtained from antibody to type III
CC       pneumococci and was isolated from the serum of a single rabbit.
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DR   PIR; A01951; KVRB2K.
DR   STRING; 9986.ENSOCUP00000003326; -.
DR   PRIDE; P01688; -.
DR   eggNOG; ENOG502S3KF; Eukaryota.
DR   Proteomes; UP000001811; Unplaced.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Immunity; Immunoglobulin;
KW   Reference proteome.
FT   CHAIN           1..>108
FT                   /note="Ig kappa chain V region K-25"
FT                   /id="PRO_0000059726"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..34
FT                   /note="Complementarity-determining-1"
FT   REGION          35..49
FT                   /note="Framework-2"
FT   REGION          50..56
FT                   /note="Complementarity-determining-2"
FT   REGION          57..88
FT                   /note="Framework-3"
FT   REGION          89..97
FT                   /note="Complementarity-determining-3"
FT   REGION          98..107
FT                   /note="Framework-4"
FT   NON_TER         108
SQ   SEQUENCE   108 AA;  11433 MW;  C16F0687550D1B6B CRC64;
     AVELTQTPAS VEAAVGGTVT IKCQASQBIY SYLSWYQQKP GQPPKLLIYK ASTLASGVSS
     RFKGSGSGTE FTLTISDLZC ADAATYYCQT YSYSSTYFGG GTEVVVKG