ID   KV1_CANLF               Reviewed;         108 AA.
AC   P01618;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Ig kappa chain V region GOM;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=100411; DOI=10.1016/0161-5890(78)90090-1;
RA   Wasserman R.L., Capra J.D.;
RT   "The amino acid sequence of the light chain variable region of a canine
RT   myeloma immunoglobulin: evidence that the VK subgroups predated mammalian
RT   speciation.";
RL   Immunochemistry 15:303-305(1978).
CC   -!- MISCELLANEOUS: Peptides were aligned by homology with human kappa
CC       chains.
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DR   PIR; A01907; K2DGGM.
DR   AlphaFoldDB; P01618; -.
DR   SMR; P01618; -.
DR   PRIDE; P01618; -.
DR   Proteomes; UP000002254; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Disulfide bond; Immunity;
KW   Immunoglobulin; Reference proteome.
FT   CHAIN           1..>108
FT                   /note="Ig kappa chain V region GOM"
FT                   /id="PRO_0000059719"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..34
FT                   /note="Complementarity-determining-1"
FT   REGION          35..49
FT                   /note="Framework-2"
FT   REGION          44..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          50..56
FT                   /note="Complementarity-determining-2"
FT   REGION          57..88
FT                   /note="Framework-3"
FT   REGION          89..97
FT                   /note="Complementarity-determining-3"
FT   REGION          98..107
FT                   /note="Framework-4"
FT   COMPBIAS        45..66
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        23..88
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         108
SQ   SEQUENCE   108 AA;  12005 MW;  02FBC498C47A3126 CRC64;
     DIVMTQTPLS LSVSPGEPAS ISCRSSQSNL DYLNWYLQKA GQSPRLLPEQ DSQRASGVPD
     RFSGSGSGTD FTLRIGRVEA EDAGIYYCMQ RSFYPYTFGQ GTRLEVRR