ID   KV2A1_MOUSE             Reviewed;         112 AA.
AC   P01626;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Ig kappa chain V-II region MOPC 167;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=99160; DOI=10.1021/bi00607a001;
RA   Rudikoff S., Potter M.;
RT   "Kappa Chain variable region from M167, a phosphorylcholine binding myeloma
RT   protein.";
RL   Biochemistry 17:2703-2707(1978).
CC   -!- MISCELLANEOUS: This chain was isolated from a myeloma protein that
CC       binds phosphorylcholine. The sequence of the V region of the heavy
CC       chain has also been determined.
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DR   PIR; A01908; KVMS16.
DR   PIR; G30538; G30538.
DR   AlphaFoldDB; P01626; -.
DR   SMR; P01626; -.
DR   MaxQB; P01626; -.
DR   PRIDE; P01626; -.
DR   MGI; MGI:3644894; EG381776.
DR   Proteomes; UP000000589; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Disulfide bond; Immunity;
KW   Immunoglobulin; Reference proteome.
FT   CHAIN           1..>112
FT                   /note="Ig kappa chain V-II region MOPC 167"
FT                   /id="PRO_0000059771"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..39
FT                   /note="Complementarity-determining-1"
FT   REGION          40..54
FT                   /note="Framework-2"
FT   REGION          55..61
FT                   /note="Complementarity-determining-2"
FT   REGION          62..93
FT                   /note="Framework-3"
FT   REGION          94..102
FT                   /note="Complementarity-determining-3"
FT   REGION          103..112
FT                   /note="Framework-4"
FT   DISULFID        23..93
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         112
SQ   SEQUENCE   112 AA;  12349 MW;  A58EDFD6404B9726 CRC64;
     DIVITQDELS NPVTSGESVS ISCRSSKSLL YKDGKTYLNW FLQRPGQSPQ LLISLMSTRA
     SGVSDRFSGS GSRTDFTLEI SRVKAEDVGV YYCQQLVEYP LTFGAGTKLE LK