ID   KV2A4_MOUSE             Reviewed;         112 AA.
AC   P01629;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Ig kappa chain V-II region 2S1.3;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=7141411; DOI=10.1515/bchm2.1982.363.2.1069;
RA   Herbst H., Chang J.Y., Aebersold R., Braun D.G.;
RT   "Murine VK25 isotype sequence: monoclonal antibody 2S1.3 specific for the
RT   group A streptococcal polysaccharide.";
RL   Hoppe-Seyler's Z. Physiol. Chem. 363:1069-1076(1982).
CC   -!- MISCELLANEOUS: This chain is from a hybridoma-derived monoclonal
CC       antibody against the streptococcal group A polysaccharide.
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DR   PIR; A01911; KVMSS1.
DR   AlphaFoldDB; P01629; -.
DR   SMR; P01629; -.
DR   PRIDE; P01629; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01629; protein.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Disulfide bond; Immunity;
KW   Immunoglobulin; Monoclonal antibody; Reference proteome.
FT   CHAIN           1..>112
FT                   /note="Ig kappa chain V-II region 2S1.3"
FT                   /id="PRO_0000059773"
FT   REGION          1..23
FT                   /note="Framework-1"
FT   REGION          24..39
FT                   /note="Complementarity-determining-1"
FT   REGION          40..54
FT                   /note="Framework-2"
FT   REGION          55..61
FT                   /note="Complementarity-determining-2"
FT   REGION          62..93
FT                   /note="Framework-3"
FT   REGION          94..102
FT                   /note="Complementarity-determining-3"
FT   REGION          103..112
FT                   /note="Framework-4"
FT   DISULFID        23..93
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         112
SQ   SEQUENCE   112 AA;  12221 MW;  BD5EF5E6D789FBEC CRC64;
     DIVMTQAAFS NPVTLGTSAS FSCRSSKSLQ QSKGITYLYW YLQKPGQSPQ LLIYQMSNLA
     SGVPDRFSGS GSGTDFTLRI SRVEAEDVGV YYCANLQELP YTFGGGTKLE IK